ArticleCureus2026
Serous Otitis Media Secondary to a Middle Ear Neuroendocrine Tumor of Five-Year Duration.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Neuroendocrine tumors (NETs) are extremely rare in the middle ear. Histopathological findings are essential to establish the definitive diagnosis of these tumors. We present the case of a 43-year-old man with a clinical diagnosis of left otitis media with effusion for five years without improvement, with a history of myringotomy with a ventilation tube. He later underwent surgery for a simple mastoidectomy with biopsy. The final diagnosis, based on histopathology and immunohistochemical studies, was a NET of the middle ear. The morphological findings of this type of tumor should be considered based on the differential diagnosis of neoplasias that develop in the middle ear; however, in many cases, the NET in this location may be underdiagnosed. The recommended treatment is surgical resection and long-term follow-up. The main objective of this article is to describe the presentation of NETs in the middle ear, although rare, to help detect more cases through education and personal experience.
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