Ultra-widefield swept-source OCT angiography assessment of choroidal changes in Chinese myopic adults.

Chao Wu, Tianwei Liu, Fengjiao Li, Wanzhen Jiao, Bojun Zhao

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Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Chao Wu *Department of Ophthalmology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.

Tianwei Liu *Department of Ophthalmology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.

Fengjiao LiDepartment of Ophthalmology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.

Wanzhen JiaoDepartment of Ophthalmology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.

Bojun ZhaoDepartment of Ophthalmology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To characterize region-specific choroidal alterations in Chinese young adults with varying refractive errors using ultra-widefield SS-OCTA (UWF SS-OCTA). Methods: In this cross-sectional study, 218 eyes from 109 participants underwent UWF SS-OCTA. Eyes were stratified by spherical equivalent (SE): low (LM), moderate (MM), and high myopia (HM). Choroidal thickness (CT), choriocapillaris vessel density (CCVD), and Sattler-Haller layer vessel density (SHVD) were quantified across nine subfields. Results: HM eyes showed significant CT reductions across all nine subfields and SHVD reductions in six subfields (all Conclusion: Region-specific reductions in CT and SHVD occurred with increasing AL. Topographic patterns-central CT thickening, inferonasal thinning, central CCVD minima, and superotemporal SHVD maxima-were preserved across myopia severities. Both CT and SHVD showed significant negative correlations with AL.

Indexed as

axial lengthchoroidal thicknessultra-widefield swept-source optical coherence tomography angiographyvessel density of the choriocapillarisvessel density of the sattler and haller layer

Identifiers

PMID42460080

DOI10.3389/fmed.2026.1863719

PMCPMC13370281

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.