ArticleJournal of biomedical optics2026
Sensor-integrated dual-clad fiber probe for OCT-guided retinal endolaser photocoagulation.
Article in Journal of biomedical optics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
Significance: Retinal endolaser photocoagulation is a widely performed vitreoretinal procedure but currently lacks real-time intraoperative feedback on treatment outcomes. Integrating optical coherence tomography (OCT) directly into the endolaser probe enables co-localized, intraoperative sensing of tissue response during laser delivery, offering the potential to significantly enhance surgical safety and efficacy. Aim: The aim of the study is to design, fabricate, and demonstrate a fiber-optic smart instrument with a 3D nano-printed microlens and instrument-integrated OCT sensing that enables co-localized, concurrent surgical laser delivery and tomographic sensing of tissue alterations during REPC. Approach: A dual-clad fiber was used to co-axially deliver surgical and OCT beams through the outer multi-mode and inner single-mode cores. A 3D nano-printed aspherical microlens ( Results: Optical performance assessments demonstrated close alignment between measured and simulated beam profiles, with an OCT spot size of Conclusions: The miniaturized iiOCT endolaser probe combines surgical laser delivery with OCT sensing, achieving adequate performance for the targeted clinical application. This sensor-integrated instrument has the potential to enable intraocular, intraoperative, and quantitative assessment of treatment outcomes. It could support feedback-driven, robotic endolaser photocoagulation, enhancing the safety and efficacy of retinal endolaser surgery.
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