Evidence map›Paper›PMID 42459967›Full record

ArticleDepression and anxiety2026

Virtual Reality for Anxiety Reduction: A Mixed-Methods Preliminary Study on Blue Space Environments Among Healthy Participants.

Adisti Dwijayanti, Aida Rosita Tantri, Dina Muktiarti, Imelda Rosalyn Sianipar, Uti Nilam Sari, Natalia Widiasih Raharjanti, Rima Maulida Hidayati, Minhua Ma

Abstract read
In one paragraph

Article in Depression and anxiety, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Adisti DwijayantiDepartment of Medical Pharmacy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, ui.ac.id.ORCID https://orcid.org/0000-0003-0612-5683
Aida Rosita TantriSimulation Based Medical Education and Research Cluster (SIMUBEAR), Indonesian Medical Education and Research Institute (IMERI), Jakarta, Indonesia.ORCID https://orcid.org/0000-0002-5535-985X
Dina MuktiartiSimulation Based Medical Education and Research Cluster (SIMUBEAR), Indonesian Medical Education and Research Institute (IMERI), Jakarta, Indonesia.ORCID https://orcid.org/0000-0002-0828-3354
Imelda Rosalyn SianiparSimulation Based Medical Education and Research Cluster (SIMUBEAR), Indonesian Medical Education and Research Institute (IMERI), Jakarta, Indonesia.ORCID https://orcid.org/0000-0002-1438-096X
Uti Nilam SariTeknologi Informasi Medimedi, Depok, Indonesia.ORCID https://orcid.org/0009-0007-6612-5171
Natalia Widiasih RaharjantiDepartment of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, ui.ac.id.ORCID https://orcid.org/0000-0002-5440-8736
Rima Maulida HidayatiSimulation Based Medical Education and Research Cluster (SIMUBEAR), Indonesian Medical Education and Research Institute (IMERI), Jakarta, Indonesia.ORCID https://orcid.org/0000-0003-1551-615X
Minhua MaDepartment of Psychiatry, University of Oxford, Oxford, UK, ox.ac.uk.ORCID https://orcid.org/0000-0001-7451-546X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Anxiety is a prevalent issue among cancer patients undergoing chemotherapy, significantly impacting their treatment and quality of life. Virtual reality (VR) has emerged as a promising nonpharmacological intervention to reduce anxiety by providing immersive, distraction-based experiences. This study introduces a VR application featuring the Seribu Islands, designed to alleviate anxiety through exposure to natural environments. Objective: To assess the effectiveness of the VR Seribu Island in reducing anxiety, evaluate user experience (UX), and identify potential cybersickness symptoms among healthy participants. Methods: A mixed-methods design was used to evaluate 30 healthy participants who interacted with the VR Seribu Island. Pre and Postexposure anxiety levels were measured using the State-Trait Anxiety Inventory (STAI). UX was assessed via a questionnaire, and semi-structured interviews explored participant perceptions. Cybersickness symptoms were evaluated using the Cybersickness Syndrome Questionnaire (CSQ-VR). Results: Post-VR anxiety scores were significantly lower than pre-VR scores (median difference = 8.0, 95% CI [4.39, 8.61], Conclusions: The VR Seribu Island significantly reduced anxiety and was well received by participants. This preliminary study supports further investigation of VR as a therapeutic tool for anxiety management in clinical populations.

Indexed as

AnxietyVirtual RealityVirtual Reality Exposure TherapyAdultFemaleHumansMaleMiddle AgedYoung Adultanxiety reductionblue spacecybersicknessuser experiencevirtual reality

Identifiers

PMID42459967
PMCPMC13371087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.