Evidence map›Paper›PMID 42459928›Full record

ReviewHealth services insights2026

Bridging Knowledge Gaps in Rheumatic Heart Disease Prevention: A Narrative Review of Educational Interventions Across Resource-Limited Settings.

Ganesh Shetty, Prashant Khadka, Dhurba Khatri, Rudra Prakash Hada, Yamuna Chhetri, Shishir Paudel, Sandeepa Karki

Abstract readReview
In one paragraph

Review in Health services insights, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ganesh ShettyKathmandu Institute of Child Health (KIOCH), Budhanilkantha Municipality, Nepal.ORCID https://orcid.org/0009-0004-4267-2670
Prashant KhadkaKathmandu Institute of Child Health (KIOCH), Budhanilkantha Municipality, Nepal.ORCID https://orcid.org/0009-0002-6515-6770
Dhurba KhatriKathmandu Institute of Child Health (KIOCH), Budhanilkantha Municipality, Nepal.ORCID https://orcid.org/0000-0001-5244-5536
Rudra Prakash HadaKathmandu Institute of Child Health (KIOCH), Budhanilkantha Municipality, Nepal.ORCID https://orcid.org/0009-0001-5796-4367
Yamuna ChhetriKathmandu Institute of Child Health (KIOCH), Budhanilkantha Municipality, Nepal.ORCID https://orcid.org/0009-0005-5534-4876
Shishir PaudelKathmandu Institute of Child Health (KIOCH), Budhanilkantha Municipality, Nepal.ORCID https://orcid.org/0000-0003-3077-6697
Sandeepa KarkiKathmandu Institute of Child Health (KIOCH), Budhanilkantha Municipality, Nepal.ORCID https://orcid.org/0000-0002-2076-5604

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) remain major public health challenges in low- and middle-income countries, where limited awareness, delayed care-seeking, and inadequate provider training contribute to preventable morbidity and mortality. Methods: A narrative review was conducted using an integrative synthesis framework to examine educational and awareness strategies implemented between 2010 and 2025. Searches across MEDLINE, Scopus, CINAHL, DOAJ, and grey literature sources identified studies reporting educational interventions targeting community members, mothers, students, or healthcare workers. Seven eligible studies were synthesised thematically based on intervention type, delivery modality, and outcomes. Result: Across the seven included studies, educational and awareness interventions consistently improved knowledge, attitudes, preventive practices, or clinical competencies related to ARF/RHD. Although study designs, target populations, and delivery modes varied widely, all interventions demonstrated positive short-term effects. Healthcare-worker programmes reported notable gains in clinical understanding and confidence, particularly regarding diagnosis and benzathine penicillin use. Maternal education improved awareness and preventive practices, while school-based sessions enhanced immediate understanding despite a gradual decline over time. Community-level mass-media campaigns achieved broad reach and generated substantial increases in both knowledge and seeking care for sore throat. Collectively, the evidence demonstrates clear beneficial trends, though long-term sustainability and comparative effectiveness remain insufficiently evaluated. Conclusion: Educational and awareness interventions consistently improve ARF/RHD-related knowledge, behaviours, and clinical competencies. Sustained impact, however, depends on integrated, multi-level approaches that combine school-based reinforcement, maternal education, health-worker training, and community-wide communication.

Indexed as

acute rheumatic feverawarenesseducationalpreventionrheumatic heart disease

Identifiers

PMID42459928
PMCPMC13369408

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.