ArticleClinical ophthalmology (Auckland, N.Z.)2026
Mechanisms of Neuroperceptual Differences Between Subjective and Objective Refraction Based on Multimodal Imaging and Neurovisual Features.
Article in Clinical ophthalmology (Auckland, N.Z.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To quantify individual variations between subjective and objective refraction, explore correlations between multimodal imaging features, clinical parameters and refraction discrepancies, screen independent influencing factors, and construct a predictive model to provide technical support for personalized refractive surgery. Methods: A total of 264 myopic patients (264 eyes) were enrolled. Paired Results: There were significant individual differences between subjective and objective refraction, and the difference distribution was consistent with the normal distribution. The difference between subjective and objective refraction was moderately correlated with long-term daily maintained refraction (r=0.47, P<0.001), weakly correlated with subjective refraction, objective refraction, corneal morphological features, and OCT optic nerve imaging features (r=0.17~0.25, P<0.05), and extremely weakly correlated or uncorrelated with OCT macular imaging features and fundus color photography imaging features (r<0.10, P>0.05). Multivariate regression analysis showed that long-term daily maintained refraction, corneal higher-order aberrations, and OCT optic nerve imaging features were independent risk factors affecting the difference (P<0.05). The prediction model constructed based on 126-dimensional radiomics key features, long-term daily maintained refraction, and core clinical parameters had a prediction accuracy of 87.2% and an area under the ROC curve (AUC) of 0.89. Conclusion: Long-term daily maintained refraction is the core factor affecting the neuroperceptual difference between subjective and objective refraction. Among multimodal imaging features, only OCT optic nerve-related features have a weak correlation with the difference, and corneal higher-order aberrations are independent influencing factors. The results of this study can provide a theoretical basis and technical support for the precise diagnosis and treatment of refractive correction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.