Evidence map›Paper›PMID 42459707›Full record

ArticleFrontiers in immunology2026

The IL-10-producing NKT10 subset plays a critical role in preventing graft-versus-host-disease.

Abel Trujillo-Ocampo, Drew Boagni, Maison Grefe, Jelita Clinton, Hong He, Ling Yu, Dan Li, Qing Ma, Seon Hee Chang, Jin S Im

Abstract read
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Abel Trujillo-OcampoDepartment of Hematopoietic Biology & Malignancies, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Drew BoagniDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Maison GrefeDepartment of Hematopoietic Biology & Malignancies, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Jelita ClintonDepartment of Therapeutic Discovery, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Hong HeDepartment of Hematopoietic Biology & Malignancies, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Ling YuDepartment of Hematopoietic Biology & Malignancies, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Dan LiDepartment of Hematopoietic Biology & Malignancies, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Qing MaDepartment of Hematopoietic Biology & Malignancies, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Seon Hee ChangDepartment of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Jin S ImDepartment of Hematopoietic Biology & Malignancies, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Kathrin Milbury · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

Invariant natural killer T (iNKT) cells play a role in preventing graft-versus-host disease (GVHD) in bone marrow transplantation (BMT), but it is not known whether and how the NKT10 and NKT17 subsets prevent GVHD. Here, we investigated the anti-GVH effects of iNKT cell subsets in a major-MHC mismatched murine BMT in which BALB/c recipients (H-2

Indexed as

Graft vs Host DiseaseInterleukin-10Natural Killer T-CellsAnimalsBone Marrow TransplantationMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutIL10 protein, mouseInterleukin-10bone marrow transplantationGvHDinvariant natural killer T cellsNKT10NKT17

Identifiers

PMID42459707
PMCPMC13368664

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.