Evidence map›Paper›PMID 42459628›Full record

ArticleFrontiers in psychology2026

The gut-brain axis and anxiety: investigating associations with diet, vigorous activity, and prior adversity.

Jenna Louise Pennella, Paul T Fuglestad

Abstract read
In one paragraph

Article in Frontiers in psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jenna Louise PennellaDepartment of Psychological and Brain Sciences, University of North Florida, Jacksonville, FL, United States.
Paul T FuglestadDepartment of Psychological and Brain Sciences, University of North Florida, Jacksonville, FL, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The current study investigated associations between different stressors (e.g., poor diet, vigorous activity, and prior adversity), GI symptoms, and anxiety. Methods: We collected survey data from a sample of university students and community participants ( Results: Key findings included: (a) vigorous activity was a significant moderator of the relationship between stress and GI symptoms; (b) GI symptoms significantly mediated the relationships between stress and anxiety and prior adversity and anxiety; (c) stress and GI symptoms were significant serial mediators of the relationships between diet quality and anxiety and prior adversity and anxiety. Discussion: Our findings suggest that factors such as adversity, diet, and physical activity levels should be considered when examining gut-brain relations specific to stress, anxiety, and GI symptoms. Future research should investigate the directionality of these relationships more clearly through longitudinal and experimental study designs.

Indexed as

anxietydietGI symptomsgut-brain axisprior adversityvigorous activity

Identifiers

PMID42459628
PMCPMC13368788

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.