ArticleClinical, cosmetic and investigational dermatology2026
Restorative Challenges: Reconstruction of Large Axillary Defects Following Surgery for Extramammary Paget's Disease.
Article in Clinical, cosmetic and investigational dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Extramammary Paget's disease (EMPD) is a rare malignant neoplasm arising from apocrine gland-bearing skin, with involvement of the axilla being particularly uncommon. Surgical excision remains the first-line treatment. However, management can be challenging because wide excision to achieve tumor-free margins may result in a large axillary defect in a high mobility region where scar contracture can compromise shoulder function. Here, we report a single case of axillary EMPD managed with surgical excision and reconstruction using a pedicled thoracodorsal artery perforator (TDAP) flap. This case highlights the pedicled TDAP flap as a reliable, muscle-sparing reconstructive option for managing large axillary defects after EMPD excision, offering favorable functional and aesthetic outcomes with minimal donor-site morbidity.
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