ArticleFrontiers in public health2026
Knowledge, attitude, and practice of central line-associated bloodstream infection prevention among intensive care unit nurses in Hebei Province, China: a cross-sectional study.
Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Central line-associated bloodstream infections (CLABSIs) are a major cause of preventable morbidity and mortality in intensive care units (ICUs). Objective: This study aimed to assess ICU nurses' knowledge, attitudes, and practices (KAP) regarding CLABSI prevention and to examine the relationships among the KAP dimensions. Methods: A cross-sectional study using convenience sampling was conducted in Chinese ICUs from January 6 to March 10, 2025. Registered ICU nurses completed a validated KAP questionnaire. After screening, 471 valid responses were analyzed (81.85% female). Knowledge (9 points), attitude (50 points), and practice (65 points) subscales were summarized using descriptive statistics. Multiple comparison corrections, Spearman correlation analysis, and structural equation modeling (SEM) were used to examine the relationships among KAP dimensions. Results: Mean (± SD) scores were knowledge 4.03 ± 1.43, attitude 43.19 ± 4.49, and practice 19.97 ± 6.66, indicating insufficient knowledge, generally positive attitudes, and inadequate preventive practices. SEM analysis showed that knowledge had a direct positive effect on attitude ( Conclusion: ICU nurses displayed positive attitudes toward CLABSI prevention but had insufficient knowledge and inadequate preventive practices. The SEM findings suggest that systemic and organizational barriers may hinder the translation of knowledge and attitude into consistent clinical practice. Targeted refresher training and institutional support are needed to improve CLABSI prevention performance.
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