ArticleJournal of surgical case reports2026
Fluoroquinolone-resistant
Article in Journal of surgical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Typhoid fever is endemic in South Asia but often overlooked or misdiagnosed in non-endemic countries like the United Arab Emirates. Intestinal perforation is a rare but life-threatening complication, and growing fluoroquinolone resistance has made empirical management more challenging. A 39-year-old male ship worker presented with generalized peritonitis after recent travel to India and had received empirical ciprofloxacin without improvement. Imaging revealed pneumoperitoneum, and laparoscopy identified a single ileal perforation 30 cm proximal to the ileocecal junction, which was repaired. Blood and stool cultures confirmed ciprofloxacin-resistant Salmonella sensitive to trimethoprim-sulfamethoxazole and meropenem. He received 7 days of intravenous meropenem followed by oral Trimethoprim-Sulfamethoxazole, resulting in complete recovery. This case highlights the importance of considering typhoid in travelers with acute abdomen, even in non-endemic regions, and emphasizes culture-guided therapy and reassessment of empirical antibiotics amid rising resistance.
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