Evidence map›Paper›PMID 42459342›Full record

Observational studyFrontiers in cellular and infection microbiology2026

Analysis of washed microbiota transplant efficacy for autism and donor-recipient gut microbiota characteristics.

Yongxi Quan, Mingming Chen, Yao Cai, Li Ling, Yedong Lao, Xingxiang He, Lihao Wu

Abstract readObservational Study
In one paragraph

Observational study in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yongxi QuanDepartment of Gastroenterology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Mingming ChenDepartment of Gastroenterology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Yao CaiDepartment of Gastroenterology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Li LingDepartment of Gastroenterology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Yedong LaoDepartment of Gastroenterology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Xingxiang HeDepartment of Gastroenterology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Lihao WuDepartment of Gastroenterology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging evidence suggests that washed microbiota transplantation (WMT) can be used to effectively treat autism spectrum disorder (ASD). This study aimed to evaluate the efficacy of WMT, investigate structural changes in the gut microbiota of children with ASD after WMT, and determine the relationship between donor and recipient gut microbiota characteristics in ASD with different treatment efficacies. This study included 38 ASD patients who underwent a full course of WMT from a single donor between July 2019 and December 2024. The clinical rating scale and stool samples were collected before and 4 weeks after WMT. Using 16S rRNA sequencing, patients were stratified by enterotype, Clinical trial registration: https://www.chictr.org.cn/index.html, identifier ChiCTR2400089296.

Indexed as

Autism Spectrum DisorderAutistic DisorderFecal Microbiota TransplantationGastrointestinal MicrobiomeBacteriaBacteroidesChildChild, PreschoolFecesFemaleHumansMalePrevotellaRNA, Ribosomal, 16STreatment OutcomeRNA, Ribosomal, 16Sautismdonor-recipiententerotypegut microbiota characteristicswashed microbiota transplantation

Identifiers

PMID42459342
PMCPMC13368480

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.