Evidence map›Paper›PMID 42459324›Full record

ArticleFrontiers in oncology2026

Case Report: Allogeneic hematopoietic stem cell transplantation in a patient with acute myeloid leukemia and hepatitis E.

Johanna Lepek, Celine Lugnier, Marie von Lilienfeld-Toal, Lukas Witkowsi, Oliver Götze, Ali Canbay, Roland Schroers, Thomas Mika

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Johanna LepekDepartment of Hematology, Oncology, Stem Cell Transplantation and Cellular Therapy, Knappschaft Kliniken Universitätsklinikum Bochum, Ruhr University, Bochum, Germany.
Celine LugnierDepartment of Hematology, Oncology, Stem Cell Transplantation and Cellular Therapy, Knappschaft Kliniken Universitätsklinikum Bochum, Ruhr University, Bochum, Germany.
Marie von Lilienfeld-ToalDepartment of Hematology, Oncology, Stem Cell Transplantation and Cellular Therapy, Knappschaft Kliniken Universitätsklinikum Bochum, Ruhr University, Bochum, Germany.
Lukas WitkowsiDepartment of Hematology and Oncology, St. Josef Hospital, Ruhr University Bochum, Bochum, Germany.
Oliver GötzeDepartment of Medicine, Knappschaft Kliniken Universitätsklinikum Bochum, Ruhr University, Bochum, Germany.
Ali CanbayDepartment of Medicine, Knappschaft Kliniken Universitätsklinikum Bochum, Ruhr University, Bochum, Germany.
Roland SchroersDepartment of Hematology, Oncology, Stem Cell Transplantation and Cellular Therapy, Knappschaft Kliniken Universitätsklinikum Bochum, Ruhr University, Bochum, Germany.
Thomas MikaDepartment of Hematology, Oncology, Stem Cell Transplantation and Cellular Therapy, Knappschaft Kliniken Universitätsklinikum Bochum, Ruhr University, Bochum, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In immunocompromised patients the Hepatitis E Virus (HEV) can lead to severe liver injury and possible liver failure. This case report describes a patient with acute myeloid leukemia in urgent need of allogeneic hematopoietic stem cell transplantation (HSCT), having symptomatic HEV infection. Prior to allogeneic HSCT, therapy with ribavirin was initiated. Urgent allogeneic HSCT was successfully performed despite persistence of HEV, with continuous ribavirin treatment during transplantation. Data regarding management of patients with HEV infection in need for HSCT is scarce. This case illustrates the feasibility of HSCT in patients with ongoing HEV-infection under continuous therapy with ribavirin.

Indexed as

acute myeloid leukemiaallogeneic stem cell transplantationAMLhepatitis EHSCT, hematopoietic stem cell transplant

Identifiers

PMID42459324
PMCPMC13371432

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.