ArticleFrontiers in oncology2026
Impact of preoperative handgrip strength and frailty on early postoperative loss of independence in patients with colorectal cancer.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aimed to identify factors associated with early postoperative loss of independence (LOI) and assess the utility of preoperative handgrip strength (HGS) and frailty evaluation among patients undergoing colorectal cancer (CRC) resection. Methods: We prospectively evaluated HGS, frailty, and depression among patients with CRC enrolled at our center from February 2024 to February 2025. The associations between HGS and perioperative outcomes were analyzed. Subsequently, a predictive model for postoperative LOI was developed based on the above three variables. Results: A total of 258 patients with CRC were enrolled, and 60 (23.3%) developed early postoperative LOI. Patients with preoperative low HGS had shorter operative time ( Conclusion: Patients with low HGS are prone to increased postoperative complications and delayed postoperative recovery. Postoperative LOI is independently correlated with ASA score ≥ 3, low HGS, and moderate frailty. Therefore, assessment of frailty and HGS prior to radical resection of CRC facilitates preoperative risk stratification.
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