Protective Effects of an Advanced Antioxidant Serum and an Encapsulated Vitamin C Serum From UV-Induced Erythema and Oxidative Stress.

Saeid Amini-Nik, Robert M Law, Vinay Bhardwaj, Stephen Lynch, Diane B Nelson

Abstract read

In one paragraph

Article in The Journal of clinical and aesthetic dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Saeid Amini-NikDr. Amini-Nik is with Société Générale de Surveillance (SGS) North America, Inc., Clinical Research, Union, New Jersey.

Robert M LawDr. Law is with the Dermatopathology Division, Sonic Healthcare USA, Dallas, Texas.

Vinay BhardwajDr. Bhardwaj is with Société Générale de Surveillance (SGS) North America, Inc., Clinical Research, Cosmetic and Personal Care, Richardson, Texas.

Stephen LynchDr. Lynch is with L'Oréal USA Research & Innovation, Clark, New Jersey.

Diane B NelsonMs. Nelson was with skinbetter science, a Dermatological Beauty Brand of L'Oréal USA, Inc.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the protective effects of 2 antioxidant products against UV light by assessing UV-induced erythema and skin damage biomarkers.

methodsA randomized, controlled trial enrolled 15 healthy women aged 35 to 60 years. Participants' lower backs were marked with 4 test sites (5 cm × 6 cm). Test products (4 mg/cm

resultsPretreatment with the advanced antioxidant serum (TAP) demonstrated 72% (1× MED, LIMITATIONS: This study was conducted in healthy participants (mean age: 49 years), with limited representation across Fitzpatrick skin types. Future studies should include a more diverse study population.

conclusionPretreatment with TAP demonstrated significantly less UV-induced erythema and provided significantly greater cellular protection vs Encap-C serum and untreated/irradiated skin.

Indexed as

MEDOxidative stressphotoprotectionskin biomarkerstopical antioxidantsUV-induced erythema

Identifiers

PMID42459249

PMCPMC13372307

What OpenQuestion holds

Textmetadata

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.