Trial reportObesity (Silver Spring, Md.)2026
Within-Day Timing of Concurrent Training Affects Inflammation and Body Composition in Young Adults With Obesity.
Trial report in Obesity (Silver Spring, Md.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveObesity is associated with chronic low-grade inflammation. Whether within-day organization of concurrent training influences inflammatory adaptation remains unclear.
methodsSixty-four young adults with obesity were randomized to continuous training (CT; high-intensity functional training immediately followed by aerobic training) or separated training (ST; the same exercise volume divided into two sessions ~6 h apart). Both groups completed an 8-week intervention. Body composition and inflammatory markers were assessed before and after training using repeated-measures ANOVA.
resultsBoth groups showed significant reductions in body mass, BMI, body fat mass, and BF% over time (all p < 0.05). Significant time × group interactions were observed for body mass, BMI, and body fat mass, with the CT group showing greater reductions than the ST group. IL-6 was the only inflammatory marker showing a significant interaction effect (p < 0.001), decreasing in CT while remaining unchanged in ST. TNF-α decreased significantly over time in both groups, whereas IL-10 and IL-1β showed no significant interaction effects.
conclusionsWithin-day continuity of concurrent training reduced fat mass more than temporally separated training in young adults with obesity. An exploratory association with reduced IL-6 was observed but requires confirmation. Trial RegistrationChinese Clinical Trial Registry identifier: ChiCTR2500108145.
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