Evidence map›Paper›PMID 42458612›Full record

SynthesisArchives of public health = Archives belges de sante publique2026

Drug sales data for gastrointestinal infections surveillance: a systematic review up to 2025.

Sofia Filippetti, Silvia Bonetta, Silvia Marro, Luisa Ceresa, Paolo Gardois, Cristina Pignata, Elisabetta Carraro

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Archives of public health = Archives belges de sante publique, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sofia FilippettiDepartment of Public Health and Pediatrics, University of Turin, Turin, Italy.
Silvia BonettaDepartment of Life Sciences and Systems Biology, University of Turin, Turin, Italy.
Silvia MarroDepartment of Prevention, Complex Structure for Hygiene in the Production of Food of Animal Origin and Their Derivatives, Turin, ASL TO5, Italy.
Luisa CeresaDepartment of Prevention, Complex Structure for Hygiene in the Production of Food of Animal Origin and Their Derivatives, Turin, ASL TO5, Italy.
Paolo GardoisFederated Library of Medicine "Ferdinando Rossi", University of Turin, Turin, Italy.
Cristina PignataDepartment of Public Health and Pediatrics, University of Turin, Turin, Italy.
Elisabetta CarraroDepartment of Public Health and Pediatrics, University of Turin, Turin, Italy. elisabetta.carraro@unito.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastrointestinal infections are an important Public Health problem. International institutions suggest supporting traditional epidemiologic surveillance with syndromic surveillance, including the use of drug sales data monitoring. This review aims to investigate the usefulness of drug sales data as a tool for gastrointestinal infections surveillance by addressing the question "could drug sales data be a complementary contribution to traditional epidemiological GI infections surveillance?".

methodsThe bibliographic search was carried out in December 2025 using a specific string across 4 scientific literature databases (PubMed, Embase, CINAHL, Cochrane Library), according to PRISMA guidelines.

resultsOut of 5.905 publications screened, 15 met the inclusion criteria and were included in the review. The selected studies were published between 1983 and 2021, mostly conducted in Europe. Despite the wide variety of study designs, 73% (n = 11) of the publications emphasized the usefulness and effectiveness of drug sales data for surveillance. In contrast, 20% (n = 3) reported no utility, and 7% (n = 1) found it to be less useful compared to other data sources. Many authors underlined the importance of considering the variables impacting the use and interpretation of drug sales data, and the importance of cooperation between healthcare providers to establish a virtuous surveillance system.

conclusionsIn the present systematic review, most selected publications seem to define drug sales data as potentially useful complementary source of information for gastrointestinal infections detection. However, heterogeneity of studies, publication bias and limitations on search strategy do not allow for a definitive qualitative conclusion. The limited number of recent studies highlights the need for further research that also considers the analysis of behavioural factors. Moreover, to optimize the use of new drug sales data collection systems for gastroenteritis surveillance, the application of new computational methods appears promising. REGISTRATION: This systematic review was recorded in the register PROSPERO (ID number CRD42023492791).

Indexed as

AntidiarrhealsAntinauseantsDrug sales dataGastrointestinal infectionsOver-the-counter drug salesPrescribed drug salesSurveillanceSyndromic surveillance

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.