Evidence map›Paper›PMID 42458607›Full record

ArticleJournal of cardiothoracic surgery2026

Contemporary outcomes of en bloc stapling of the pulmonary artery, bronchus, and lymph nodes during lobectomy for non-small cell lung cancer: a retrospective study.

Keiji Yamanashi, Ryo Miyata, Takeshi Kawaguchi, Masatsugu Hamaji

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Article in Journal of cardiothoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Keiji YamanashiDepartment of Thoracic and Cardiovascular Surgery, School of Medicine, Nara Medical University, 840 Shijo-Cho Kashihara, Nara, 634-8522, Japan. jiike6180@kuhp.kyoto-u.ac.jp.
Ryo MiyataDepartment of Thoracic and Cardiovascular Surgery, School of Medicine, Nara Medical University, 840 Shijo-Cho Kashihara, Nara, 634-8522, Japan.
Takeshi KawaguchiDepartment of Thoracic and Cardiovascular Surgery, School of Medicine, Nara Medical University, 840 Shijo-Cho Kashihara, Nara, 634-8522, Japan.
Masatsugu HamajiDepartment of Thoracic and Cardiovascular Surgery, School of Medicine, Nara Medical University, 840 Shijo-Cho Kashihara, Nara, 634-8522, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study investigates the safety and postoperative outcomes of en bloc stapling of the pulmonary artery branches, bronchial branches, and lymph nodes using an auto-stapler during lobectomy for non-small cell lung cancer.

methodsA retrospective chart review was conducted to identify consecutive patients who underwent lobectomy for non-small cell lung cancer with en bloc stapling of the pulmonary artery branches, bronchial branches, and lymph nodes using an auto-stapler between 2019 and 2024. Patient characteristics, perioperative outcomes, and long-term survival rates were analyzed.

resultsEighteen patients were included, with the median age of 76.5 years and the median follow-up of 35.1 months. Thirteen patients underwent complete resection, whereas five patients had incomplete resection due to adherent metastatic lymph nodes around the pulmonary artery and bronchus. The incidences of grade ≥ 3 intraoperative and postoperative complications were 0% and 11%, respectively, with no procedure-related events such as bronchovascular fistula. The five-year overall survival rates in patients who underwent complete and incomplete resections were 44.0% and 50.0%, respectively. Among patients with incomplete resection, four experienced disease progression, and two died of lung cancer. Two patients receiving targeted therapies remained alive at 31.4 and 73.8 months postoperatively, without any evidence of disease progression.

conclusionsEn bloc stapling of the pulmonary artery branches, bronchial branches, and lymph nodes using an auto-stapler during lobectomy for non-small cell lung cancer may represent a feasible bailout option in selected patients in whom separate hilar dissection and division are technically difficult or potentially hazardous. Even in cases involving lymph node metastases near the stapling site, multimodal therapy guided by genetic profiling of surgical specimens may contribute to acceptable long-term outcomes in carefully selected patients.

trial registrationNot applicable.

Indexed as

BronchiCarcinoma, Non-Small-Cell LungLung NeoplasmsLymph NodesPneumonectomyPulmonary ArterySurgical StaplingAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesSurvival RateTreatment OutcomeBronchusEn bloc staplingLobectomyNon-small cell lung cancerPulmonary artery

Identifiers

PMID42458607
PMCPMC13651168

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