ArticleParasites & vectors2026
Asynchronous local differences in Lyme disease environmental hazard driven by variation in tick abundance and Borrelia burgdorferi infection prevalence.
Article in Parasites & vectors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThe tick-borne disease Lyme borreliosis (LB) is a clear and increasing public health threat across the temperate regions of the northern hemisphere, including the United Kingdom. The epidemiology of LB is shaped by the environmental hazard posed by its causative agent Borrelia burgdorferi sensu lato, which is frequently quantified in terms of the density of infected nymphal ticks (DIN).
methodsWe report quantification of the dynamics of DIN at three sites in close proximity to one another in Cumbria, a region of the UK where LB is frequently reported, through monthly surveys of questing Ixodes ricinus nymphs over a 33-month period.
resultsDespite the proximity of study sites, we observed significant spatial variation in DIN between them. We also observed significant temporal variation in DIN at all three sites, but this variation was asynchronous. Changes in both tick abundance and B. burgdorferi infection prevalence underlay this variation.
conclusionsThese observations suggest very local key ecological determinants of DIN and that meaningful estimation/prediction of LB risk on a national or regional scale is extremely challenging.
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