Evidence map›Paper›PMID 42458552›Full record

ArticleScandinavian journal of trauma, resuscitation and emergency medicine2026

Geographical alignment of prehospital critical care services with population need for out-of-hospital cardiac arrest patients.

Adam J Boulton, Nigel Lang, Joshua Miller, Gregory Adam Whitley, Oliver Zorab, Adam de Paeztron, Caroline Leech, Paramjit Gill, Gavin D Perkins, João Porto de Albuquerque and 2 more

Abstract read
In one paragraph

Article in Scandinavian journal of trauma, resuscitation and emergency medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Adam J BoultonWarwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, CV4 7AL, UK. a.boulton@warwick.ac.uk.
Nigel LangDevon Air Ambulance, Exeter, UK.
Joshua MillerWest Midlands Ambulance Service University NHS Foundation Trust, Brierley Hill, UK.
Gregory Adam WhitleyClinical Audit and Research Unit, East Midlands Ambulance Service NHS Trust, Lincoln, UK.
Oliver ZorabSouth Western Ambulance Service NHS Foundation Trust, Exeter, UK.
Adam de PaeztronOut-of-Hospital Cardiac Arrest Outcome (OHCAO) Project, Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK.
Caroline LeechWarwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, CV4 7AL, UK.
Paramjit GillWarwick Applied Health, Medical School, University of Warwick, Coventry, UK.
Gavin D PerkinsWarwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, CV4 7AL, UK.
João Porto de AlbuquerqueUrban Big Data Centre, School of Social and Political Sciences, University of Glasgow, Glasgow, G12 8QQ, Scotland, UK.
Terry P BrownOut-of-Hospital Cardiac Arrest Outcome (OHCAO) Project, Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK.
Joyce YeungWarwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, CV4 7AL, UK.

Funding

National Institute for Health and Care Research NIHR303023
6 · The paper itself

Abstract

backgroundPrehospital critical care is associated with improved outcomes following out-of-hospital cardiac arrest (OHCA), but may not be distributed equitably.

aimTo examine the alignment between prehospital critical care provision and neighbourhood OHCA risk, predicted survival, and deprivation across three neighbouring ambulance regions in England.

methodsData on all OHCAs treated by three neighbouring English ambulance services (2018-2023) were aggregated to the neighbourhood level. Prehospital critical care response time predictions were generated from service-supplied operational parameters and calibrated against observed data with rural-urban adjustment. High-risk neighbourhoods were defined by above-median OHCA incidence and below-median bystander CPR. Pre-EMS predicted survival was estimated using a published model. Deprivation was measured with Index of Multiple Deprivation. Weighted regression models with service-by-response time interaction terms examined each neighbourhood metric per 5-minute response time increase. A secondary analysis examined a HEMS-only configuration by removing the unique urban, NHS car asset in service B.

resultsOverall, 52.9% of the resident population and 51.3% of OHCAs were within 15 min of a prehospital critical care response. In two services, increasing response time was associated with higher odds of a neighbourhood being high-risk and with greater deprivation. For pre-EMS predicted survival, poor alignment was found in one service, favourable alignment in another, and no significant association in the third. Service B showed favourable alignment across all three metrics. Removing the urban car asset (HEMS-only configuration) reversed this favourable pattern, producing gradients consistent with the other two services. Sensitivity analysis using observed response times and distances produced consistent but attenuated associations.

conclusionPrehospital critical care provision, particularly HEMS, is generally poorly aligned with neighbourhood OHCA risk, pre-EMS predicted survival, and deprivation. The only region demonstrating favourable cardiac arrest alignment was attributable to its urban NHS car asset. Expanding car-based prehospital critical care in deprived urban areas may warrant consideration as a strategy to reach more OHCA patients and improve equity of access.

Indexed as

Critical CareEmergency Medical ServicesOut-of-Hospital Cardiac ArrestAgedCardiopulmonary ResuscitationEnglandFemaleHumansMaleAdvanced life supportAir ambulanceEmergency medical servicesGeographic information systemsHealth inequalitiesHealth inequitiesPrehospital physicianResource allocationResuscitationSocioeconomic factors

Identifiers

PMID42458552
PMCPMC13660141

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.