Evidence map›Paper›PMID 42458513›Full record

Observational studySubstance abuse treatment, prevention, and policy2026

Is routine screening for substance use disorders useful in palliative care? Results of a prospective observational study.

Christian Volberg, Katharina Toussaint, Jorge Riera-Knorrenschild, Felix Carl Fabian Schmitt, Astrid Morin, Martin Gschnell, Nils Heuser

Abstract readObservational Study
In one paragraph

Observational study in Substance abuse treatment, prevention, and policy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christian VolbergMarburg University, Department of Anesthesiology and Intensive Care Medicine, University Hospital of Marburg, Baldingerstraße, 35043, Marburg, Germany. christian.volberg@staff.uni-marburg.de.ORCID http://orcid.org/0000-0002-2008-0197
Katharina ToussaintMarburg University, Department of Anesthesiology and Intensive Care Medicine, University Hospital of Marburg, Baldingerstraße, 35043, Marburg, Germany.
Jorge Riera-KnorrenschildMarburg University, Department of Haematology, Oncology and Immunology, University Hospital of Marburg, Marburg, Germany.
Felix Carl Fabian SchmittMarburg University, Department of Anesthesiology and Intensive Care Medicine, University Hospital of Marburg, Baldingerstraße, 35043, Marburg, Germany.
Astrid MorinMarburg University, Department of Anesthesiology and Intensive Care Medicine, University Hospital of Marburg, Baldingerstraße, 35043, Marburg, Germany.
Martin GschnellMarburg University, Department of Dermatology and Allergology, University Hospital of Marburg, Marburg, Germany.
Nils HeuserMarburg University, Department of Anesthesiology and Intensive Care Medicine, University Hospital of Marburg, Baldingerstraße, 35043, Marburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSubstance use disorders are an increasingly prevalent issue in today's society, and they can be caused by prescription of drugs with addictive potential. Patients with incurable diseases often experience severe symptoms and require medications with the potential to cause dependence. For patients with a predisposition to addiction, this can lead to the development of a substance use disorder, further reducing their quality of life. METHODOLOGY: Over a period of six months, all patients newly admitted to the palliative care unit were screened for unusual medication use. If the initial survey, which used the 'Short Questionnaire on Medication Use', revealed abnormal results, the WHO-ASSIST V3.0 questionnaire was administered to identify substance use disorders and the extent of dependence.

resultsA total of 181 patients were admitted to the palliative care unit during the survey period. Of these, the initial screening could not be performed in 119 patients (65.7%) due to accompanying circumstances. Of the 62 patients who were included in the study, 15 (24.2%) had an elevated score on the 'Short Questionnaire on Medication Use'. The WHO-ASSIST V3.0 questionnaire indicated positive consumption of alcohol in 100% of cases, opioids in 86.7% of cases, tobacco in 73.3% of cases, and sedatives and sleeping pills in 53.3% of cases. Most respondents were at moderate risk of dependence, with only one person at high risk of opioid use. However, further treatment for a substance use disorder was not deemed to be clinically relevant for any of the patients.

conclusionThis survey found that routinely screening palliative care patients for substance use disorders did not provide any clinically relevant information for further treatment of the examined cohort. Given the high level of stress often experienced by people with incurable diseases, the extent to which screening is helpful or merely an unnecessary burden should be considered. As other surveys have shown that palliative care patients with substance use disorders benefit from treatment, follow-up studies should investigate how to identify patients at risk specifically.

Indexed as

Mass ScreeningPalliative CareSubstance-Related DisordersAdultAgedFemaleHumansMaleMiddle AgedProspective StudiesSurveys and Questionnaires

Identifiers

PMID42458513
PMCPMC13383392

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.