Evidence map›Paper›PMID 42458477›Full record

ArticleMolecular cancer2026

Mutation-specific dynamics of dedifferentiation trajectories and tumor-stromal interactions in thyroid cancer.

Eun Hye Joo, Young Shin Song, Han Sai Lee, Gyeongseo Jung, Eun-Jae Chung, Su-Jin Kim, Yoo Hyung Kim, Sun Wook Cho, Hongyoon Choi, Jae-Kyung Won and 2 more

Abstract read
In one paragraph

Article in Molecular cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Eun Hye Joo *Genomic Medicine Institute Medical Research Center, Seoul National University College of Medicine, Seoul, Republic of Korea.
Young Shin Song *Department of Internal Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Republic of Korea.
Han Sai LeeDepartment of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea.
Gyeongseo JungDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Eun-Jae ChungDepartment of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital and College of Medicine, Seoul, Republic of Korea.
Su-Jin KimDepartment of Surgery, Seoul National University Hospital and College of Medicine, Seoul, Republic of Korea.
Yoo Hyung KimDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Sun Wook ChoDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Hongyoon ChoiDepartment of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Jae-Kyung WonDepartment of Pathology, Seoul National University Hospital and College of Medicine, Seoul, Republic of Korea. jkwon@snuh.org.
Woong-Yang ParkDepartment of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences & Technology, Sungkyunkwan University, Seoul, Republic of Korea. woongyang.park@samsung.com.
Young Joo ParkGenomic Medicine Institute Medical Research Center, Seoul National University College of Medicine, Seoul, Republic of Korea. yjparkmd@snu.ac.kr.

Funding

Korea Institute for Advancement of Technology RS-2025-02303021National Research Foundation of Korea RS-2024-00453506
6 · The paper itself

Abstract

Progression from differentiated thyroid cancer to anaplastic thyroid cancer (ATC) involves profound epithelial plasticity and remodeling of the tumor microenvironment (TME), but how BRAF

Indexed as

Cell DedifferentiationMutationStromal CellsThyroid NeoplasmsTumor MicroenvironmentEpithelial-Mesenchymal TransitionGene Expression Regulation, NeoplasticHumansProto-Oncogene Proteins B-rafSignal TransductionThyroid Carcinoma, AnaplasticProto-Oncogene Proteins B-raf

Identifiers

PMID42458477
PMCPMC13374302

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.