ArticleBMC pediatrics2026
Comparative analysis of chlamydia pneumoniae pneumonia and Mycoplasma pneumoniae pneumonia in children.
Article in BMC pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundChlamydia pneumoniae pneumonia (CPP) in children often presents with mild clinical manifestations, leading to less clinical attention. This study aimed to compare the clinical features of Mycoplasma pneumoniae pneumonia (MPP) and CPP in pediatric patients and to identify risk factors for lobar involvement in CPP.
methodsWe conducted a retrospective analysis of 145 children with CPP and 145 contemporaneously hospitalized children with MPP. Clinical characteristics were compared between the two groups. Patients with CPP were further stratified into lobar pneumonia and bronchopneumonia subgroups to assess risk factors for lobar consolidation.
resultsChildren with CPP were significantly older than those with MPP 11.00(8.33-12.42)years vs. 6.20 (4.00-8.00)years, p < 0.05). The CPP group exhibited lower peak fever, shorter febrile duration, a higher incidence of chest pain, and lower rates of tachypnea and hypoxemia (all p < 0.05). Laboratory findings showed significantly higher eosinophil counts and lower levels of C-reactive protein (CRP), procalcitonin (PCT), and lactate dehydrogenase (LDH) in CPP patients compared to MPP patients (all p < 0.05). Lobar pneumonia accounted for 61.4% of CPP cases. On binary logistic regression analysis, decreased breath sounds was identified as a risk factor for lobar involvement in CPP.
conclusionsCompared to MPP, CPP patients is characterized by more frequent chest pain, lower inflammatory marker, and higher eosinophil counts. The presence of decreased breath sounds may serve as a clinical indicator for lobar pneumonia in children with C. pneumoniae infection.
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