Evidence map›Paper›PMID 42458268›Full record

ArticleBMC genomics2026

Genome-wide comparison of traditional and commercial Mehraban sheep populations reveals differences in genetic structure, linkage disequilibrium, and inbreeding patterns.

Leyla Eskandari, Ahmad Ahmadi, Reza Talebi, Masoumeh Naserkheil, Seyyedeh Azadeh Javadi Taklimi, Fatemeh Zare, Tomasz Szmatoła, Masoud Shirali, Mohammad Reza Ghaffari

Abstract readComparative Study
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In one paragraph

Article in BMC genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Leyla EskandariDepartment of Animal Sciences, Faculty of Agriculture, Bu-Ali Sina University, Hamedan, Iran.
Ahmad AhmadiDepartment of Animal Sciences, Faculty of Agriculture, Bu-Ali Sina University, Hamedan, Iran. ahmadi@basu.ac.ir.
Reza TalebiDepartment of Animal Genomics and Bioinformatics, Animal Biotechnology Research Institute, Agricultural Biotechnology Research Institute of Iran (ABRII), Agricultural Research, Education and Extension Organization (AREEO), Rasht, Iran. talere1986@gmail.com.ORCID http://orcid.org/0000-0002-5555-8453
Masoumeh NaserkheilDepartment of Animal Breeding and Genetic, Animal Science Research Institute of Iran (ASRII), Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran.
Seyyedeh Azadeh Javadi TaklimiDepartment of Animal Genomics and Bioinformatics, Animal Biotechnology Research Institute, Agricultural Biotechnology Research Institute of Iran (ABRII), Agricultural Research, Education and Extension Organization (AREEO), Rasht, Iran.
Fatemeh ZareDepartment of Animal Genomics and Bioinformatics, Animal Biotechnology Research Institute, Agricultural Biotechnology Research Institute of Iran (ABRII), Agricultural Research, Education and Extension Organization (AREEO), Rasht, Iran.
Tomasz SzmatołaDepartment of Basic Sciences, University of Agriculture in Kraków, Al. Mickiewicza 24/28, Kraków, 30-059, Poland.ORCID http://orcid.org/0000-0003-1588-4198
Masoud ShiraliSchool of Biological Sciences, Queen's University Belfast, Belfast, BT9 5DL, UK.
Mohammad Reza GhaffariDepartment of Systems and Synthetic Biology, Agricultural Biotechnology Research Institute of Iran (ABRII), Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran.ORCID http://orcid.org/0000-0002-7139-8613

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the genetic architecture of sheep under different breeding systems is crucial for enhancing productivity and maintaining adaptive capacity. We analyzed 145 Mehraban sheep from commercial (n = 97) and traditional (n = 48) populations utilizing the OvineSNP50 BeadChip array. The analysis revealed that the linkage disequilibrium (LD) was numerically higher on average in the traditional population at both short and long distances (mean r² = 0.249 at < 10 kb; 0.037 at 5 Mb) in comparison to the commercial population (mean r² = 0.220 and 0.027, respectively), suggesting a smaller historical effective population size (Ne). Principal component and admixture analyses validated strong genetic difference, with the commercial population showing moderate admixture from traditional lines. Principal component and admixture analysis confirmed significant genetic difference, with the commercial population exhibiting considerable admixture from traditional lines. Analysis of runs of homozygosity (ROH) revealed more numerous and longer ROH segments in commercial animals (total ROH ~ 43,768 Mb, F

Indexed as

GenomeInbreedingLinkage DisequilibriumAnimalsFemaleGenetics, PopulationPolymorphism, Single NucleotidePrincipal Component AnalysisQuantitative Trait LociSheepAdmixture analysisAutozygosityBeadChip arrayGenetic diversity

Identifiers

PMID42458268

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.