Evidence map›Paper›PMID 42458191›Full record

ArticleApplied psychophysiology and biofeedback2026

Synergy and Synchrony Between Beta-Theta Neurofeedback, Heart Rate Variability Biofeedback and Breathwork Via Continuous Feedback in Improving Reaction Time.

Mahdi Zolfagharzadeh-Kermani

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Article in Applied psychophysiology and biofeedback, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

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1 author.

Mahdi Zolfagharzadeh-KermaniDepartment of Biomedical Engineering, SR.C, Islamic Azad University, Tehran, Iran. m.zolfagharzadehkermani@iau.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, the applied psychophysiology community has started to investigate the effectiveness of combining neurofeedback and biofeedback interventions. The training triad of beta-theta neurofeedback, heart rate variability biofeedback, and box-breathing continuous feedback can influence participants' electrophysiological activity and also help healthy individuals decrease reaction time. For this purpose, twenty-two students (6 male, 16 female) were randomly assigned to three experimental groups using block randomization. The first group (N = 7) received 10 sessions of beta-theta neurofeedback, heart rate variability biofeedback, and box-breathing continuous feedback simultaneously. The second group (N = 8) underwent 10 sessions of only box-breathing continuous feedback, while the third group (N = 7) participated in 10 sessions of beta-theta neurofeedback and heart rate variability biofeedback together. A multivariate analysis of covariance was used to compare reaction time scores among the three groups in a pretest-posttest design. Additionally, repeated measures analysis of variance assessed within-group changes in electrophysiological markers across three time points: pre-test, mid-test, and post-test. Results indicated that, compared to groups 2 and 3, the visual-recognition-reaction-time scores in experimental group 1 significantly decreased (P-value < 0.05). In addition, group 1 showed significant within-group changes (P-value  < 0.05) in electroencephalography measures (beta/theta power ratio and high-beta relative power) and heart rate variability (root mean square of successive differences). We conclude that the combination of beta-theta neurofeedback, heart rate variability biofeedback, and box-breathing continuous feedback can effectively reduce reaction time through mind-body interaction at a self-aware level.

Indexed as

Box-breathing continues feedbackHRV biofeedbackMind-body interactionNeurofeedbackOperant conditioningReaction time

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.