Evidence map›Paper›PMID 42458149›Full record

ArticleParasitology research2026

Quinolones as anti-Toxoplasma agents: a comprehensive scoping review of in vitro and in vivo efficacy.

Maryam Hataminejad, Marzieh Asadi, Saeed Emami, Moozhan Mofidi, Mahbobeh Montazeri

Abstract readScoping Review
PubMed Publisher
In one paragraph

Article in Parasitology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maryam HataminejadToxoplasmosis Research Center, Communicable Disease Institute, Mazandaran University of Medical Sciences, Km 18, Farah-Abad Road, P.O Box: 48471-91971, Sari, Iran.
Marzieh AsadiToxoplasmosis Research Center, Communicable Disease Institute, Mazandaran University of Medical Sciences, Km 18, Farah-Abad Road, P.O Box: 48471-91971, Sari, Iran.
Saeed EmamiDepartment of Medicinal Chemistry and Pharmaceutical Sciences Research Center, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
Moozhan MofidiStudent Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.
Mahbobeh MontazeriToxoplasmosis Research Center, Communicable Disease Institute, Mazandaran University of Medical Sciences, Km 18, Farah-Abad Road, P.O Box: 48471-91971, Sari, Iran. m.montazeri2012@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxoplasmosis is a globally prevalent parasitic disease with significant therapeutic limitations, especially in vulnerable populations. This scoping review assesses the efficacy of quinolones against Toxoplasma gondii in vitro and in vivo. PubMed, ScienceDirect, Web of Science, Embase, Scopus, ProQuest, and Google Scholar were searched from inception to August 2024. Original English-language studies evaluating quinolone effects on T. gondii were included. Screening and data extraction followed PRISMA 2020 guidelines. Of 5,252 initial records, 29 studies were shortlisted for final qualitative synthesis. In vitro analysis revealed a stark dichotomy: while clinical fluoroquinolones such as ciprofloxacin (IC

Indexed as

Antiprotozoal AgentsQuinolonesToxoplasmaToxoplasmosisAnimalsHumansAntiprotozoal AgentsQuinolonesDrugsFluoroquinolonesQuinolonesToxoplasma gondiiToxoplasmosis

Identifiers

PMID42458149

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.