Evidence map›Paper›PMID 42457569›Full record

ArticleAnnals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia2026

A Novel Method for Predicting Recirculation by Sweep-Gas Control in Extracorporeal Membrane Oxygenation.

Tomoki Tahara, Daisuke Sakota, Nobutomo Morita, Ryo Kosaka, Katsuhiro Ohuchi, Tetsuhito Kigata, Yusuke Tsuboko, Tomoyuki Fujita, Eiki Nagaoka

Abstract readValidation Study
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In one paragraph

Article in Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tomoki TaharaDepartment of Cardiovascular Surgery, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Daisuke SakotaHealth and Medical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan.
Nobutomo MoritaSensing System Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Tosu, Saga, Japan.
Ryo KosakaHealth and Medical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan.
Katsuhiro OhuchiDepartment of Clinical Engineering, Faculty of Medical Science, Juntendo University, Tokyo, Japan.
Tetsuhito KigataDepartment of Anatomy and Neurobiology, National Defense Medical College, Tokorozawa, Saitama, Japan.
Yusuke TsubokoDivision of Medical Devices, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan.
Tomoyuki FujitaDepartment of Cardiovascular Surgery, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Eiki NagaokaDepartment of Cardiovascular Surgery, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRecirculation is a critical issue in veno-venous extracorporeal membrane oxygenation (VV ECMO). We propose a novel method for estimating the recirculation ratio using temporary sweep-gas control.

methodsA circuit simulating VV ECMO recirculation was constructed by introducing a short circuit between the inlet and outlet of the oxygenator, enabling direct measurement of recirculation flow. Temporary cessation of sweep gas induced decreases in oxygen saturation at the oxygenator inlet (S

resultsIn circuit experiments, the relative prediction error was 7.0% ± 5.2%. Early prediction required 3.0 ± 1.0 s when recirculation was ≤50% and 4.1 ± 1.0 s when >50%. In animal experiments, the error was 7.5% ± 4.0%, with times of 10.4 ± 2.8 s for recirculation ≤50% and 27.8 ± 0.5 s for >50%.

conclusionsThe proposed method enables rapid, less invasive prediction of the recirculation ratio and may provide a practical tool for optimizing ECMO management.

Indexed as

Extracorporeal Membrane OxygenationModels, CardiovascularOxygenAnimalsEquipment DesignModels, AnimalOxygenators, MembraneOxygen SaturationPredictive Value of TestsReproducibility of ResultsSus scrofaSwineTime FactorsOxygencardiopulmonary bypassextracorporeal membrane oxygenationhemodynamicsmedical devicesrecirculation

Identifiers

PMID42457569
PMCPMC13377292

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.