Evidence map›Paper›PMID 42457568›Full record

ArticleAnnals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia2026

Safety and Feasibility of a Simplified Perioperative Hemodialysis Protocol in Hemodialysis Patients Undergoing Off-Pump Coronary Artery Bypass Grafting.

Toshio Doi, Saori Nagura, Kanetsugu Nagao, Masaya Aoki, Shigeki Yokoyama, Shigeyuki Yamashita, Kazuaki Fukahara, Naoki Yoshimura

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Article in Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Toshio DoiFirst Department of Surgery, University of Toyama, Toyama, Toyama, Japan.ORCID http://orcid.org/0000-0002-0764-1519
Saori NaguraFirst Department of Surgery, University of Toyama, Toyama, Toyama, Japan.
Kanetsugu NagaoFirst Department of Surgery, University of Toyama, Toyama, Toyama, Japan.
Masaya AokiFirst Department of Surgery, University of Toyama, Toyama, Toyama, Japan.
Shigeki YokoyamaFirst Department of Surgery, University of Toyama, Toyama, Toyama, Japan.
Shigeyuki YamashitaFirst Department of Surgery, University of Toyama, Toyama, Toyama, Japan.
Kazuaki FukaharaDepartment of Surgery, Imizu Municipal Hospital, Toyama, Toyama, Japan.
Naoki YoshimuraFirst Department of Surgery, University of Toyama, Toyama, Toyama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePatients on hemodialysis (HD) undergoing coronary artery bypass grafting (CABG) face a high risk of perioperative complications, and the optimal timing of perioperative HD remains unclear. We evaluated the safety and feasibility of a standardized HD protocol in patients undergoing off-pump CABG (OPCAB).

methodsWe retrospectively analyzed 64 HD-dependent patients who underwent elective OPCAB at a single institution between March 2014 and December 2024. The protocol included maintaining a Monday-Wednesday-Friday HD schedule, performing routine HD on Monday morning, conducting OPCAB on Monday afternoon, and resuming HD on postoperative day (POD) 2. Clinical outcomes, unplanned dialysis, and perioperative biochemical changes were assessed.

resultsSeven patients (10.9%) required unplanned renal replacement therapy before the first postoperative HD session for congestive heart failure (n = 3), hyperkalemia (n = 3), or respiratory failure (n = 1). None required additional dialysis after the initial postoperative HD. In-hospital mortality was 3.1%. Postoperative congestive heart failure occurred in 4.7% of patients. Body weight returned to near baseline by POD 7, and serum potassium remained within an acceptable range throughout the perioperative period.

conclusionThis standardized perioperative HD protocol was feasible for maintenance HD patients undergoing elective OPCAB. However, protocol deviation in 10.9% of patients suggests that further refinement and prospective comparative studies are warranted.

Indexed as

Coronary Artery Bypass, Off-PumpCoronary Artery DiseaseRenal DialysisAgedFeasibility StudiesFemaleHospital MortalityHumansMaleMiddle AgedPerioperative CareRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment Outcomeend-stage renal diseaseoff-pump coronary artery bypass graftingperioperative hemodialysis management

Identifiers

PMID42457568
PMCPMC13384733

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.