ArticleThe Journal of veterinary medical science2026
Gut microbiome changes in a captive giant panda with cardiovascular disease.
Article in The Journal of veterinary medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The interaction between gut bacteria and their host is vital for the early diagnosis and treatment of disease in captive animals. Here, we report a 16S rRNA sequencing-based bacterial profile during the progression of cardiovascular disease and drug treatment in a captive giant panda (Ailuropoda melanoleuca). We observed changes in the composition of bacteria associated with inflammation and regulating nutrient metabolism. Predicted metabolic functions also exhibited alterations. The remarkably reduced gut microbiome diversity, along with the imbalance in community interaction networks, indicated possible gut dysfunction. Our findings represent the first description of gut bacterial changes in a giant panda with cardiovascular disease. Maintaining symbiotic bacteria diversity is crucial for preventing health issues in captive animals and advancing wildlife conservation efforts.
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