Evidence map›Paper›PMID 42457214›Full record

ArticleRMD open2026

Epidemiology of idiopathic inflammatory myopathies: a population-based cohort in England, 2002-2021.

Patrick Gordon, Michael McLean, Maciej Czachorowski, Jason Xenakis, Anna Barkaway, Saqib Rana, Serhan Bahit, Charlotte Curtis, Jennifer Hannah, James Galloway

Abstract read
In one paragraph

Article in RMD open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Patrick GordonDepartment of Academic Rheumatology, King's College London, London, UK.
Michael McLeanPfizer Ltd, Tadworth, UK.
Maciej CzachorowskiPfizer Ltd, Tadworth, UK.
Jason XenakisPfizer Ltd, Tadworth, UK.
Anna BarkawayPfizer Ltd, Tadworth, UK.ORCID http://orcid.org/0000-0003-4366-0378
Saqib RanaPfizer Ltd, Tadworth, UK.
Serhan BahitMomentum Data Ltd, St. Albans, UK.
Charlotte CurtisMomentum Data Ltd, St. Albans, UK.ORCID http://orcid.org/0000-0002-1022-3887
Jennifer HannahDepartment of Academic Rheumatology, King's College London, London, UK.
James GallowayDepartment of Academic Rheumatology, King's College London, London, UK james.galloway@kcl.ac.uk.ORCID http://orcid.org/0000-0002-1230-2781

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIdiopathic inflammatory myopathies (IIM) are a heterogenous group of conditions with substantial morbidity but population-based epidemiology is lacking. We aimed to provide a contemporary epidemiological assessment of IIM.

methodsPopulation-based study using the Clinical Practice Research Datalink (CPRD) Aurum primary care database with linkage to hospital episode data. All patients (aged >2 years) from England registered between 1 March 2002 and 31 March 2021 were included. Incidence was estimated for three main IIM subtypes: dermatomyositis (DM), inclusion body myositis (IBM) and other IIM. Incidence rate ratios using Poisson models were compared across subgroups.

resultsWe identified n=1590 DM, n=432 IBM and n=2083 other IIM incident cases. Incidence of DM was 0.79 (95% CI 0.75 to 0.83), IBM 0.50 (95% CI 0.46 to 0.55) and other IIM 1.03 (95% CI 0.99 to 1.08) per 100 000 person-years.Females had a higher incidence of DM (adjusted incidence rate ratio (aIRR) 1.84, 95% CI 1.66 to 2.04) and other IIM (aIRR 1.09, 95% CI 1.00 to 1.19), but a lower incidence of IBM (aIRR 0.73, 95% CI 0.60 to 0.89), compared with males. South Asian, black, other and unknown ethnic groups had a higher incidence of DM and other IIM compared with those of white ethnicity, particularly individuals of black ethnicity for other IIM (aIRR 2.80, 95% CI 2.32 to 3.37).Point prevalence at study end was 0.015% for DM, 0.005% for IBM and 0.016% for other IIM.

conclusionThere are major demographic differences in IIM incidence, notably by sex and ethnicity. Resource planning should account for these marked differences.

Indexed as

MyositisAdolescentAdultAgedChildChild, PreschoolDermatomyositisEnglandFemaleHumansIncidenceMaleMiddle AgedPopulation SurveillanceYoung AdultDermatomyositisEpidemiologyIncidencePrevalence

Identifiers

PMID42457214
PMCPMC13374478

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.