Evidence map›Paper›PMID 42457202›Full record

Trial reportJournal of clinical periodontology2026

Peri-Implant Soft Tissue Response to Monolithic Zirconia Versus Porcelain-Fused-to-Metal Implant Crowns: Histological and Clinical Outcomes of an RCT.

Yifan Zhang, Sven Mühlemann, Aspasia Pachiou, Stephanie Astrid Stalder, Ronald E Jung, Ye Lin, Daniel S Thoma

Registry-linked trialAbstract readRandomized Controlled TrialComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of clinical periodontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02272491 (Monolithic Zirconia Crowns for Single Implants in the Molar Region), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02272491 naactive not recruitingnot on this map

Monolithic Zirconia Crowns for Single Implants in the Molar Region: a Randomized Controlled Clinical Trial

TypeinterventionalSponsorUniversity of ZurichRan2014 to 2027Enrolled83ConditionsImplant-supported Single CrownsArmsZrO2 (Straumann CARES), PFM crown (Straumann Gold)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yifan ZhangDepartment of Implantology, Peking University School and Hospital of Stomatology, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China.ORCID https://orcid.org/0000-0003-0701-3771
Sven MühlemannClinic of Reconstructive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0003-1253-1813
Aspasia PachiouClinic of Reconstructive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland.
Stephanie Astrid StalderClinic of Reconstructive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland.
Ronald E JungClinic of Reconstructive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland.
Ye LinDepartment of Implantology, Peking University School and Hospital of Stomatology, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China.
Daniel S ThomaClinic of Reconstructive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-1764-7447

Funding

Clinic of Reconstructive Dentistry, Center of Dental Medicine, University of Zurich, SwitzerlandInstitut Straumann AGITI Foundation 937_2014National Natural Science Foundation of China 82401062
6 · The paper itself

Abstract

objectiveTo assess the peri-implant soft-tissue and hard-tissue response to monolithic zirconia (ZrO

methodsThis report constitutes a pre-specified secondary analysis of this RCT. Eighty-three patients rehabilitated with single-tooth implants in the molar region were originally randomly assigned to receive either a ZrO

resultsThe present exploratory secondary analysis included 67 patients (37 ZrO

conclusionMonolithic zirconia and PFM implant-supported single crowns resulted in comparable clinical and radiographic outcomes. The peri-implant soft-tissue response to the two restorative materials showed a greater effect of the tissue region, while the material itself had only negligible effect.

trial registrationClinicalTrials.gov identifier: NCT02272491.

Indexed as

CrownsDental Implants, Single-ToothDental PorcelainDental Prosthesis, Implant-SupportedMetal Ceramic AlloysPeriodontiumZirconiumAdultAgedConnective TissueDental MaterialsDental Prosthesis DesignEpithelial AttachmentFemaleFibroblastsGingivaDental MaterialsDental PorcelainMetal Ceramic AlloysZirconiumzirconium oxidedental implantshistologymonolithic zirconiaperi‐implant soft tissueporcelain fused to metal

Identifiers

PMID42457202
PMCPMC13477850

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.