Evidence map›Paper›PMID 42456283›Full record

ArticleClinical practice and cases in emergency medicine2025

The Trigeminocardiac Reflex? Severe Bradycardia Secondary to Facial Trauma: A Case Report.

Boris Penev, Hallmon Hughes, Katherine Scarpino, Daniel J Ritter

Abstract readCase Reports
In one paragraph

Article in Clinical practice and cases in emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Boris PenevMedical University of South Carolina, Department of Emergency Medicine, Charleston, South Carolina.
Hallmon HughesMedical University of South Carolina, College of Medicine, Charleston, South Carolina.
Katherine ScarpinoMedical University of South Carolina, Department of Emergency Medicine, Charleston, South Carolina.
Daniel J RitterMedical University of South Carolina, Department of Emergency Medicine, Charleston, South Carolina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe trigeminocardiac reflex (TCR), a physiologic response to irritation of the branches of the trigeminal nerve, was first described in humans in 1870. Gastric hypermotility, hypotension, bradycardia, and even asystole have been reported in response to surgical manipulation of the trigeminal nerve and its branches, but literature is limited in patients not undergoing surgery. Although effects are generally transient and benign, TCR can present a significant diagnostic and therapeutic challenge in patients undergoing surgical manipulation of the trigeminal nerve and its branches. CASE REPORT: We describe a case of severe bradycardia secondary to facial trauma causing hemodynamic compromise and diagnostic uncertainty.

conclusionThis case highlights a possible case of TCR, as well as therapeutic considerations, in a patient presenting to the emergency department with severe facial trauma.

Identifiers

PMID42456283
PMCPMC12342677

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.