Evidence map›Paper›PMID 42455949›Full record

ArticleScience advances2026

Heterochronic limb patterning in marsupials reveals flexibility in the processes underlying lateral plate mesoderm morphogenesis.

Axel H Newton, Alexandra Leggatt, Ella R Farley, Karen E Sears, Aidan M Couzens, Sara Ord, Andrew J Pask

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Axel H NewtonThe School of BioSciences, University of Melbourne, Victoria, 3010, Australia.ORCID 0000-0001-7175-5978
Alexandra LeggattThe School of BioSciences, University of Melbourne, Victoria, 3010, Australia.ORCID 0009-0008-7121-1530
Ella R FarleyThe School of BioSciences, University of Melbourne, Victoria, 3010, Australia.ORCID 0009-0006-6254-4654
Karen E SearsDepartment of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA.ORCID 0000-0001-9744-9602
Aidan M CouzensDepartment of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA.
Sara OrdColossal BioSciences, Dallas, TX 75247, USA.ORCID 0009-0005-1630-0803
Andrew J PaskThe School of BioSciences, University of Melbourne, Victoria, 3010, Australia.ORCID 0000-0002-1900-2263

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marsupial embryos develop under intense functional constraints: neonates are born after a short gestation but must immediately crawl to the teat using precociously developed forelimbs. To meet this demand, marsupials have evolved extreme acceleration of limb morphogenesis, yet the cellular and molecular mechanisms underlying this shift remain unresolved. Using two distantly related marsupials, the fat-tailed dunnart (

Indexed as

Body PatterningExtremitiesMarsupialiaMesodermMorphogenesisAnimalsForelimbGene Expression Regulation, Developmental

Identifiers

PMID42455949
PMCPMC13371925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.