Evidence map›Paper›PMID 42455893›Full record

ArticleScience advances2026

Structure and dynamics of a four-protofilament microtubule from Heimdallarchaeales α/β-tubulin.

Linh T Tran, Samson Ali, Tomoharu Matsumoto, Yosuke Yamazaki, Akihiro Narita, Makito Miyazaki, Robert C Robinson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Linh T TranRIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.ORCID 0000-0003-0654-6517
Samson AliResearch Institute for Interdisciplinary Science, Okayama University, Okayama 700-8530, Japan.ORCID 0000-0002-1410-990X
Tomoharu MatsumotoDepartment of Biological Science, Graduate School of Science, Nagoya University, Nagoya, Aichi 464-8601, Japan.ORCID 0000-0002-5417-5514
Yosuke YamazakiRIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.ORCID 0000-0002-6863-3344
Akihiro NaritaDepartment of Biological Science, Graduate School of Science, Nagoya University, Nagoya, Aichi 464-8601, Japan.ORCID 0000-0003-1504-9352
Makito MiyazakiRIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.ORCID 0000-0002-4603-851X
Robert C RobinsonResearch Institute for Interdisciplinary Science, Okayama University, Okayama 700-8530, Japan.ORCID 0000-0001-6367-6903

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eukaryotic microtubules are typically 13-protofilament tubes assembled from α/β-tubulin heterodimers that combine mechanical rigidity with dynamic instability. Homologous tubulins have been identified in Asgard archaea, the closest prokaryotic relatives to eukaryotes. Here, we characterize a heterodimeric α/β-tubulin system from Heimdallarchaeales. Biochemical reconstitution shows that

Indexed as

ArchaeaMicrotubulesTubulinCryoelectron MicroscopyGuanosine TriphosphateModels, MolecularPolymerizationProtein MultimerizationGuanosine TriphosphateTubulin

Identifiers

PMID42455893
PMCPMC13371889

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.