ArticleScience advances2026
On-demand growth of semiconductor heterostructures guided by physics-informed machine learning.
Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
18 authors.
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Abstract
Developing tailored heterostructures on demand is essential to meet the growing needs of semiconductor devices. However, traditional methods remain constrained by simulation-based design and iterative trial-and-error optimization. Here, we introduce SemiEpi, a self-driving platform designed for molecular beam epitaxy (MBE) that enables multi-step semiconductor heterostructure growth through in situ Reflection High Energy Electron Diffraction monitoring and on-the-fly feedback control. By integrating MBE reactors, physics-informed machine learning (ML) models, and parameter initialization, SemiEpi designs heterostructures, identifies optimal initial conditions, and proposes experiments for material growth. As a demonstration, we optimized high-density InAs quantum dot growth with a target emission wavelength of 1240 nm, achieving a density of 5 × 10
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Registered trials
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