ArticleVeterinary medicine and science2026
In Vitro Antiparasitic Effects of Silver Nanoparticles on Sarcocystis Bradyzoites.
Article in Veterinary medicine and science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundSarcocystis is a protozoan parasite of significant zoonotic and economic importance, primarily transmitted through the consumption of contaminated meat. Conventional antiparasitic drugs show limited efficacy and potential side effects, leading to growing interest in nanotechnology-based alternatives.
objectiveThis study evaluated the in vitro antiparasitic activity of silver nanoparticles (AgNPs) against Sarcocystis bradyzoites isolated from sheep.
methodsMacroscopic cysts were collected from infected sheep muscles at the Tabriz abattoir, and bradyzoites were purified and confirmed to be viable using trypan blue staining and a bioassay in cats. The parasites were exposed to AgNP concentrations of 100, 200, 400 and 800 µg/mL for 10, 30, 60 and 120 min, in triplicate. Untreated samples (phosphate-buffered saline [PBS]) and 5% NaCl (positive control) were included for comparison. Data were analysed using one-way ANOVA (p < 0.05).
resultsThe results demonstrated that a dose- and time-dependent increase in mortality, ranging from 20.11% ± 2.49% at 100 µg/mL after 10 min to 59.53% ± 8.52% at 800 µg/mL after 120 min. Although silver nanoparticles (AgNPs) did not achieve complete inactivation, their significant effect compared to controls (p < 0.05) indicates moderate in vitro antiparasitic activity.
conclusionAgNPs exhibited measurable in vitro antiparasitic activity against Sarcocystis bradyzoites, suggesting their promise as an adjunct or alternative to traditional drugs. Further in vivo studies are recommended to assess safety, optimal dosing and practical applications in veterinary and food safety contexts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.