ReviewRadiologie (Heidelberg, Germany)2026
[Metabolism and bone marrow : Imaging of physiological and pathological processes].
Review in Radiologie (Heidelberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
clinical/methodical issueHuman bone marrow and its metabolism-particularly the composition of bone marrow adipose tissue (BMAT)-are subject to physiological changes throughout the lifespan. However, they are also involved in and altered by pathological processes. Modern techniques of quantitative magnetic resonance imaging (MRI) now enable an objective and quantitative evaluation of such processes. STANDARD RADIOLOGICAL
methodsStandard radiological procedures consist of T1- and T2-weighted MRI of the bone (marrow). METHODICAL INNOVATIONS: Methodological innovations consist of chemical shift encoding-based (CSE) water-fat imaging and proton ( PERFORMANCE: In particular, quantification using the proton density fat fraction (PDFF) is of relevance for both physiological and pathological changes of BMAT. ACHIEVEMENTS: The determination of the PDFF-particularly by means of ( PRACTICAL RECOMMENDATIONS: Knowledge of the typical signal characteristics of BMAT is essential for reliably discriminating physiological from pathological changes-both in terms of visual image reading and quantification.
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