Evidence map›Paper›PMID 42455304›Full record

ArticleCurrent microbiology2026

Comparative Genomic Analysis of the Type VI Secretion System in Strains of the Rhizobium leguminosarum Species Complex with Variable Host Specificity.

Olga A Pavlova, Alexandra V Dolgikh, Alexandra A Shalyakina, Elizaveta A Salnikova, Alina M Dymo, Tatyana S Aksenova, Oksana N Kurchak, Olga P Onishchuk, Elena A Dolgikh

Abstract readComparative Study
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In one paragraph

Article in Current microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Olga A PavlovaLaboratory of Signal Regulation, All-Russia Research Institute for Agricultural Microbiology, St.-Petersburg, Russia.
Alexandra V DolgikhLaboratory of Signal Regulation, All-Russia Research Institute for Agricultural Microbiology, St.-Petersburg, Russia.
Alexandra A ShalyakinaLaboratory of Signal Regulation, All-Russia Research Institute for Agricultural Microbiology, St.-Petersburg, Russia.
Elizaveta A SalnikovaLaboratory of Signal Regulation, All-Russia Research Institute for Agricultural Microbiology, St.-Petersburg, Russia.
Alina M DymoLaboratory of Signal Regulation, All-Russia Research Institute for Agricultural Microbiology, St.-Petersburg, Russia.
Tatyana S AksenovaLaboratory of Signal Regulation, All-Russia Research Institute for Agricultural Microbiology, St.-Petersburg, Russia.
Oksana N KurchakLaboratory of Signal Regulation, All-Russia Research Institute for Agricultural Microbiology, St.-Petersburg, Russia.
Olga P OnishchukLaboratory of Signal Regulation, All-Russia Research Institute for Agricultural Microbiology, St.-Petersburg, Russia.
Elena A DolgikhLaboratory of Signal Regulation, All-Russia Research Institute for Agricultural Microbiology, St.-Petersburg, Russia. ea.dolgikh@arriam.ru.ORCID http://orcid.org/0000-0002-5375-0943

Funding

Russian Science Foundation RSF 24-16-00180
6 · The paper itself

Abstract

In this study, genes encoding components of the type VI (T6SS) secretion system and putative effectors were searched in rhizobial strains belonging to the Rhizobium leguminosarum species complex. For this purpose, the genome assembly of the new Rhizobium laguerreae Wp19 strain (genospecies N) isolated from wild pea nodules was done and compared to the type strains. Comparative analysis of tss gene clusters was conducted in the new Wp19 strain and other R. laguerreae strains, as well as R. ruizarguesonis and R. johnstonii strains with available genomes. The resulting genome assemblies of R. laguerreae Wp19 and other strains were analyzed to compare the homology of genes that encode the T6SS proteins - tssI (VrgG) and tssD (Hcp). A detailed study of their genomic environment revealed a number of genes that encode putative effector proteins. Among the identified proteins, some are conserved, such as proteins with the DUF2169 (adaptor), and DUF4150 domains, while others are found only in individual strains (e.g., proteins consisting of 358/360 and 309/310 amino acids in R. johnstonii 3841, R. ruizarguesonis UPM1133, and R. beringeri SM51). In contrast, the effector protein consisting of 197 amino acids was found in almost all R. laguerreae strains, which may be related to its specific function in these strains.

Indexed as

Genome, BacterialHost SpecificityRhizobium leguminosarumType VI Secretion SystemsBacterial ProteinsGenomicsMultigene FamilyPhylogenyPisum sativumRoot Nodules, PlantBacterial ProteinsType VI Secretion Systems

Identifiers

PMID42455304

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