ArticleRadiological physics and technology2026
Coplanar versus non-coplanar volumetric modulated arc therapy for hippocampal avoidance whole brain radiotherapy using Monte Carlo-based planning system.
Article in Radiological physics and technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
This retrospective study evaluates the dosimetric performance of coplanar versus non-coplanar volumetric modulated arc therapy (VMAT) for hippocampal avoidance whole-brain radiotherapy (HA-WBRT) using the Monaco treatment planning system. Ten patients were replanned using four techniques: three coplanar configurations with two, three, and four arcs, and one plan with both coplanar and non-coplanar arcs. A prescription of 30 Gy in 10 fractions was delivered to the planning target volume (PTV). Increasing the number of coplanar arcs improved target coverage and homogeneity, with the four-arc coplanar plan achieving PTV coverage, conformity, and homogeneity comparable to the non-coplanar approach. All techniques met protocol constraints for hippocampal and organ-at-risk doses, although non-coplanar VMAT produced the lowest absolute hippocampal doses. Non-coplanar plans required higher monitor units and longer treatment times. Four-arc coplanar VMAT demonstrated comparable dosimetric performance with improved delivery efficiency, supporting its use as a practical alternative in settings where non-coplanar delivery is limited.
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