ArticleIrish journal of medical science2026
Holmium laser lithotripsy and its effects on postoperative complications in urolithiasis.
Article in Irish journal of medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveThis study investigated the impact of holmium laser lithotripsy on the incidence of postoperative complications in patients with urolithiasis.
methodsThis study was a retrospective cohort study. A total of 115 patients diagnosed with urolithiasis and treated at our hospital were enrolled. According to the surgical procedure used, patients were assigned to a control group [n = 57, received extracorporeal shock wave lithotripsy (ESWL)], and a study group (n = 58, underwent holmium laser lithotripsy]. Baseline characteristics were compared. Postoperative complication rates, treatment efficacy, operative indicators (operative time, hematuria volume within 24 h postoperatively, time to first ambulation, and hospital stay), and levels of inflammatory markers (C-reactive protein [CRP], procalcitonin [PCT]), and renal function indicators (serum creatinine [Scr]) were measured before surgery and one day postoperatively.
resultsNo significant differences were noted in baseline characteristics between the two groups (P > 0.05). The study group demonstrated a lower incidence of postoperative complications, a higher overall effective treatment rate, as well as lower operative time, hematuria volume within 24 h postoperatively, time to first ambulation, and length of hospital stay (P < 0.05) relative to the control group. One day post-surgery, CRP, PCT, and Scr levels increased in both groups relative to preoperative values (P < 0.05), but the elevations were significantly lower in the study group (P < 0.05).
conclusionHolmium laser lithotripsy effectively decreases the incidence of postoperative complications in patients with urolithiasis, improves therapeutic outcomes, reduces surgical trauma, alleviates postoperative inflammatory responses, and mitigates renal functional impairment.
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