Evidence map›Paper›PMID 42455234›Full record

ReviewHealth economics review2026

Establishing multiple cost-effectiveness thresholds in Oman: a stakeholder-driven approach.

Said Wani, Hilal Alsabti, Said Allamki, Ahmed Almandhari, Suleiman Alhajji, Ibrahim Alrashdi, Raid Alsabri, Adnan Alqassabi, Ahmed Alzaabi, Aisha Almaashani and 21 more

Abstract readReview
In one paragraph

Review in Health economics review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Methodological guidelines for Health Technology Assessment in Oman.Journal of pharmaceutical policy and practice · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Said WaniCenter for Health Technology Assessment, Semmelweis University, Ulloi ut 25, Budapest, 1085, Hungary. said.rashdi@phd.semmelweis.hu.ORCID http://orcid.org/0009-0008-7337-494X
Hilal AlsabtiMinistry of Health, Muscat, Oman.
Said AllamkiMinistry of Health, Muscat, Oman.
Ahmed AlmandhariMinistry of Health, Muscat, Oman.
Suleiman AlhajjiMinistry of Health, Muscat, Oman.
Ibrahim AlrashdiMinistry of Health, Muscat, Oman.
Raid AlsabriMinistry of Health, Muscat, Oman.
Adnan AlqassabiRoyal Hospital, Ministry of Health, Muscat, Oman.
Ahmed AlzaabiPharmacy Department, Ministry of Health, Sohar, Oman.
Aisha AlmaashaniSultan Qaboos Hospital, Ministry of Health, Salalah, Oman.
Alia AlshuailiMinistry of Health, Muscat, Oman.
Anisa RasoolMinistry of Health, Muscat, Oman.
Asiya AlkindiMinistry of Health, Muscat, Oman.
Bushra SalmanPharmacy Department, National Hematology and Bone Marrow Transplant Center, University Medical City, Seeb, Oman.
Faiza AlzadjaliMedical Devices Control Department, Drug Safety Center, Ministry of Health, Muscat, Oman.
Khalid AlrahbiPharmacy Department, Sumail Hospital, Ministry of Health, Sumail, Oman.
Khulood AlmutawaKhoula Hospital, Ministry of Health, Muscat, Oman.
Manal AlansariMinistry of Health, Muscat, Oman.
Mardheya AlkharusiClinical Pharmacy, Al Nahdha Hospital, Khoula Hospital, Ministry of Health, Muscat, Oman.
Nadiya AlbulushiPharmaceutical Care Department, Ministry of Health, Muscat, Oman.
Rahma AlghadaniMinistry of Health, Rustaq, Oman.
Rana AljaberPharmacy Support Services, Sultan Qaboos Comprehensive Cancer Care and Research Centre , University Medical City, Seeb, Oman.
Safiya AlmuainiMinistry of Health, Muscat, Oman.
Said AlkindiKhoula Hospital, Ministry of Health, Muscat, Oman.
Salim AlzawamriMinistry of Health, Salalah, Oman.
Sara AlbalushiMinistry of Health, Muscat, Oman.
Suha AllawatiPharmaceutical Care Department, Ministry of Health, Muscat, Oman.
Zuhair AlsaltiMinistry of Health, Muscat, Oman.
Hassan AlbalushiDepartment, Ibri Hospital, Ministry of Health, Ibri, Oman.
Ahmad Nader FasseehSyreon Middle East, Alexandria, Egypt.
Zoltan KaloCenter for Health Technology Assessment, Semmelweis University, Ulloi ut 25, Budapest, 1085, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe rising cost of new health technologies and limited healthcare budgets challenge health systems worldwide, including Oman. Local value judgments are crucial for informed decision-making. This study aims to establish a cost-effectiveness thresholds (CETs) framework for Oman, aligned with the country's economic status and healthcare priorities.

methodsThe key findings from a recent literature review on global CETs and their applications were shared and discussed during a multi-stakeholder workshop in March 2024. Presenting these findings has provided participants a broad understanding of global CET practices and highlighted the use of multiple thresholds across different settings. Afterwards, a survey was distributed, asking participants to anonymously vote on six key concepts: the basis for the threshold, the baseline threshold multiplier, the use of multiple thresholds, the criteria for multiple thresholds, the number of multipliers, and which criterion should receive the 3X multiplier. The results from this voting guided the design and final agreement on the threshold values.

resultsTwenty respondents supported adopting multiple CET values based on cost per quality-adjusted life-year (QALY), linked to Oman's economic status. A baseline CET equal to 1x Gross Domestic Product (GDP) per capita was suggested. Participants recommended three different threshold multipliers to reflect policy priorities. A continuous multiplier (1-3x GDP), based on incremental QALY gains, was used to favor technologies with greater health gains. Additionally, a fixed multiplier of 2 was chosen for both orphan drugs and treatments for priority diseases. The resulting CET values reflect technical and expert consensus and do not include patient or public perspectives.

conclusionsIn Oman, the incremental cost per QALY gained should not exceed 1x GDP per capita for new health technologies that offer minimal health gains in common diseases. However, thresholds might increase to 12x GDP per capita for curative treatments in rare priority disease areas. It is recommended that CET values be reviewed and updated within three years, based on initial implementation experiences.

Indexed as

CETCost-effectiveness thresholdCost-effectiveness threshold multiplierEconomic evaluationHealth technology assessmentMultiple thresholdsOman

Identifiers

PMID42455234
PMCPMC13656365

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.