ArticleMolecular biology reports2026
DNA methylation diversity analysis in the cashew germplasm accessions.
Article in Molecular biology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEpigenetic diversity plays an important role in the phenotypic variations of plants, and an understanding of it can facilitate crop improvement. However, epigenetic variations in cashew have not been explored. METHODS AND
resultsDNA methylation patterns were analysed in 24 cashew accessions using the amplified methylation polymorphism polymerase chain reaction (AMP-PCR), which captures methylation-sensitive CCGG-containing loci. Overall DNA methylation across the assayed loci was 47.85%, comprising 25.35% hemimethylation and 22.49% full methylation. Methylation sensitive markers were highly informative, with mean polymorphic information content (PIC), effective multiplex ratio (EMR), and discriminating power (D) of 0.35, 2.51 and 0.86, respectively. Methylation frequency varied from 13.59% to 48.37%, suggesting substantial epigenetic variability among the accessions. The mean epigenetic distance (0.76) among the accessions was considerably higher than the mean genetic distance (0.18). Unweighted Pair Group Method with Arithmetic Mean (UPGMA) clustering based on the epigenetic distances differed from clustering based on genetic distances. Principal coordinate analysis explained 29.76% of the total epigenetic variation across the first three axes, and analysis of molecular variance (AMOVA) analysis showed that 89% of the variation was partitioned within populations. Epigenetic diversity showed a weakly positive correlation with phenotypic diversity of nine yield-related traits (r = 0.15), while it was weakly negative between genetic variations and phenotypic diversity (r = 0.12).
conclusionsThe study demonstrates that substantial epigenetic variation exists in the evaluated cashew germplasm and suggests that DNA methylation may contribute to phenotypic differentiation. These findings provide new insights into epigenetic diversity and highlight its potential utility in germplasm characterization and crop improvement.
Indexed as
Identifiers
42455205What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.