Evidence map›Paper›PMID 42455158›Full record

ArticleSurgery today2026

Does graft implantation sequence affect post-transplant outcome in simultaneous pancreas-kidney transplantation? An analysis of a nationwide registry in Japan.

Yoshito Tomimaru, Toshinori Ito, Yoshimitsu Shimomura, Tetsuhisa Kitamura, Takashi Kenmochi, Yuichiro Doki, Hidetoshi Eguchi

Abstract read
PubMed Publisher
In one paragraph

Article in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yoshito TomimaruDepartment of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2 Yamadaoka E-2, Suita, 565-0871, Osaka, Japan.
Toshinori ItoThe Japan Pancreas Transplant Registry, Society for Pancreas and Islet Transplantation, Suita, Japan.
Yoshimitsu ShimomuraDivision of Environmental Medicine and Population Sciences, Department of Social and Environmental Medicine, The University of Osaka, Suita, Japan.
Tetsuhisa KitamuraDivision of Environmental Medicine and Population Sciences, Department of Social and Environmental Medicine, The University of Osaka, Suita, Japan.
Takashi KenmochiThe Japan Pancreas Transplant Registry, Society for Pancreas and Islet Transplantation, Suita, Japan.
Yuichiro DokiDepartment of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2 Yamadaoka E-2, Suita, 565-0871, Osaka, Japan.
Hidetoshi EguchiDepartment of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, 2-2 Yamadaoka E-2, Suita, 565-0871, Osaka, Japan. heguchi@gesurg.med.osaka-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposesSimultaneous pancreas-kidney transplantation (SPK) is an effective treatment for type 1 diabetes and end-stage renal disease. However, whether the graft implantation sequence influences the outcomes remains unclear. This study aimed to clarify the impact of implantation order on graft and patient outcomes using data from the Japanese Pancreas Transplant Registry.

methodsWe retrospectively analyzed consecutive patients with SPK during the study period. Patients were categorized into pancreas-first (P-first) or kidney-first (K-first) groups based on the ischemic time of each graft. The outcomes assessed included graft loss, graft survival, and patient survival. Kaplan-Meier and multivariate Cox regression analyses were used to compare the groups. Subgroup analyses were also performed, including assessments of transfer time.

resultsAmong 449 SPK recipients, 346 were in the K-first group and 103 in the P-first group. No significant differences were observed between the groups with regard to pancreatic or kidney graft loss, graft survival, or patient survival. These findings remained consistent across all subgroup analyses and in models that used transfer time as a continuous variable.

conclusionsThe graft implantation sequence did not significantly affect graft or patient outcomes following SPK. The order can be chosen based on surgeon preference or institutional protocols, without compromising the prognosis.

Indexed as

Graft lossGraft survivalImplantation sequencePancreas transplantationTransfer time

Identifiers

PMID42455158

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.