Chronic Total Occlusion After Kawasaki Disease.

Juliana Gomez-Arostegui, Jane C Burns, Jiken Bhatt, Kirsten B Dummer

Abstract readCase Reports

In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Juliana Gomez-ArosteguiDepartment of Pediatrics, University of California-San Diego, San Diego, California, USA; Pediatric Cardiology, Rady Children's Hospital, San Diego, California, USA. Electronic address: jgomezarostegui1@rchsd.org.

Jane C BurnsDepartment of Pediatrics, University of California-San Diego, San Diego, California, USA; Kawasaki Disease Research Center, La Jolla, California, USA.

Jiken BhattSan Diego Cardiac Center Medical Group, San Diego, California, USA.

Kirsten B DummerDepartment of Pediatrics, University of California-San Diego, San Diego, California, USA; Pediatric Cardiology, Rady Children's Hospital, San Diego, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKawasaki disease (KD) is the most common acquired heart disease in children. Coronary artery aneurysms (CAAs) occur in 25% of untreated and 5% of treated cases. Large CAAs increase the risk for thrombosis, myocardial ischemia, and chronic total occlusion (CTO). Patients with collateral formation may remain asymptomatic.

methodsAfter retrospective chart review, we describe 8 patients diagnosed with CTO between ages 2 to 50 years following childhood KD.

resultsAll patients developed giant CAAs after KD. Four pediatric patients presented with CTO between ages 2 to 16 years. Four adults had childhood KD that was untreated or managed before standardized treatment and were lost to follow-up until CTO diagnosis between ages 31 to 50 years. Three patients had surgical bypass.

conclusionsPatients with KD and large CAAs remain at lifelong risk for thrombosis and CTO. Collateralization from slow, chronic ischemia may allow for conservative management in asymptomatic patients.

Indexed as

acute coronary syndromecoronary artery bypasscoronary calcium scoreperfusion

Identifiers

PMID42455094

DOI10.1016/j.jaccas.2026.109296

PMCPMC13531212

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