Evidence map›Paper›PMID 42454907›Full record

ArticleMicrobiology spectrum2026

Host interactomes of

Axel Larsson, Yashuan Chao, Oonagh Shannon, Lotta Happonen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Axel LarssonSection for Oral Biology and Pathology, Faculty of Odontology, Malmö University, Malmö, Sweden.ORCID 0009-0005-6154-2334
Yashuan ChaoSection for Oral Biology and Pathology, Faculty of Odontology, Malmö University, Malmö, Sweden.ORCID 0000-0002-0295-3142
Oonagh ShannonSection for Oral Biology and Pathology, Faculty of Odontology, Malmö University, Malmö, Sweden.
Lotta HapponenDivision of Infection Medicine, Department of Clinical Sciences, Faculty of Medicine, Lund University, Lund, Sweden.ORCID 0000-0002-5922-4549

Funding

Alfred Österlunds StiftelseKungliga Fysiografiska Sällskapet i LundStiftelsen för Kunskaps- och Kompetensutveckling 20250008Vetenskapsrådet 2022-03860
6 · The paper itself

Abstract

Oral streptococci colonize the oral cavity in multispecies communities. They adhere to the salivary pellicle through surface interactions, whereafter additional bacteria and fungi are recruited to form the stable community. The oral streptococci reside as commensals in the oral cavity and contribute to homeostasis, for example, through colonization resistance. However, accumulation of bacteria at the gingival margins can cause inflammation in the oral cavity, leading to increased interaction with inflammatory mediators and serum constituents from the blood. Furthermore, mechanical disruption of the gingiva can allow oral streptococci to spread to the blood, cause bacteremia, and, in some cases, severe systemic disease such as infective endocarditis. To better understand the adaptation to niches mimicking oral homeostasis and inflammation, we describe the growth and viability of two commensal oral streptococci-

Indexed as

SalivaSerumStreptococcal InfectionsStreptococcus gordoniiStreptococcus oralisHumansMouthProteomicshost interactomeoral homeostasisoral streptococciproteomicssalivaserumStreptococcus gordoniiStreptococcus oralis

Identifiers

PMID42454907
PMCPMC13436360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.