ArticleRevista da Associacao Medica Brasileira (1992)2026
Evaluation of routine four-quadrant re-excision in patients undergoing breast-conserving surgery.
Article in Revista da Associacao Medica Brasileira (1992), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveThe aim of this study was to evaluate the contribution of routine four-quadrant re-excision performed during breast-conserving surgery in detecting de novo tumor foci and ensuring negative surgical margins in patients with breast cancer.
methodsA retrospective analysis was conducted on 44 female patients who underwent breast-conserving surgery between April 2021 and April 2023. In all cases, routine re-excision was performed in the superior, inferior, medial, and lateral quadrants during the same operative session. Based on pathological findings, patients with additional tumor foci in the re-excision specimens were classified as Group 1, while those without were classified as Group 2.
resultsThe mean age of the patients was 54.2±11.6 years, with an average follow-up period of 21.5±8.3 months. Additional tumor foci were identified in seven patients (15.9%). There were no statistically significant differences between the groups in terms of age, tumor size, hormone receptor status, or histopathological characteristics (p>0.05).
conclusionRoutine four-quadrant re-excision may aid in the identification of microscopic de novo tumor foci even when clear surgical margins are achieved. However, larger multicenter studies with longer follow-up periods are warranted to determine its potential impact on local recurrence and long-term outcomes.
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