ArticleClinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery2026
Nocturnal Hypoxemia Burden Correlates With Vestibular Dysfunction in Obstructive Sleep Apnea.
Article in Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionObstructive sleep apnea (OSA) is a potential contributor to vestibular dysfunction, though specific correlating parameters remain unclear. This study aimed to determine whether hypoxemia severity indices correlate quantitatively with caloric slow-phase eye velocity (SPV), a marker of vestibular function.
methodsIn a retrospective cohort of 82 adults undergoing both full-night PSG and bithermal caloric testing, the primary outcome was total caloric SPV (°/s; sum of four irrigations). Fifteen prespecified predictors were evaluated, including hypoxemia burden (apnea-hypopnea index [AHI], oxygen desaturation index [ODI], cumulative time with SpO
resultsSPV was inversely correlated with AHI (r = -0.295, p = 0.007), ODI (r = -0.261, p = 0.018) and CT90 (r = -0.254, p = 0.021). Sleep efficiency, snoring index, pulse rate, nadir SpO
conclusionNocturnal hypoxemia burden-reflecting the frequency and cumulative duration of oxygen desaturation-emerged as the principal predictor of reduced caloric SPV in patients with OSA. While the low explained variance of our models (R
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