ArticleJournal of child psychology and psychiatry, and allied disciplines2026
Cognitive reappraisal modulates neural responses to aversive sensory stimulation in autistic youth.
Article in Journal of child psychology and psychiatry, and allied disciplines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundSensory over-responsivity (SOR) is highly prevalent and impairing in autism spectrum disorder (ASD). SOR has been associated with sensory-limbic hyperresponsivity and reduced prefrontal top-down regulation during sensory stimulation. There are few evidence-based treatments for SOR, but cognitive reappraisal, an emotion regulation strategy, has been shown to reduce negative feelings through activation of frontal brain regions. The current study examined whether reappraisal changes neural reactivity to aversive sensory stimulation in autistic compared to typically developing (TD) children.
methodsForty-seven ASD and 45 age/IQ-matched TD youth aged 8-15 years participated in fMRI while experiencing aversive tactile stimulation on their arm and alternately focused either on how the stimulus made them feel ('React'), or how they would describe the stimuli objectively ('Reappraise'). Aversiveness ratings were provided after each stimulus. Parents reported on participants' SOR severity.
resultsAutistic youth showed reduced activation in sensory cortical regions during Reappraisal compared to React. Reappraisal also resulted in increased dorsomedial prefrontal cortex activation, with a trend toward more increases in the TD group but no significant group differences. Despite these reappraisal-related neural changes across both groups, only TD youth showed a reduction in aversiveness ratings for Reappraisal compared to React. Among ASD youth, higher SOR was associated with fewer decreases in sensory cortices but greater increases in frontal regions during Reappraisal compared to React. Older ASD youth also showed increased activity in the ventral prefrontal cortex during Reappraisal.
conclusionsResults suggest that cognitive reappraisal modulates neural responses during sensory processing and, more specifically, may reduce hyperactivity in sensory cortical regions previously shown to be associated with SOR. However, individual differences such as age and SOR severity may affect the extent to which top-down cognitive processes are uniquely engaged during reappraisal.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.