ArticleInternational journal of general medicine2026
Elevated Red Cell Distribution Width as a Potential Marker of Acute Mountain Sickness in Chinese Young Men Upon Rapidly Ascending to 3,650 m.
Article in International journal of general medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Elevated red cell distribution width (RDW) has been implicated in chronic mountain sickness; however, its relationship with acute mountain sickness (AMS) remains uncertain. We aimed to evaluate the association between elevated RDW and AMS among Chinese young men undergoing high-altitude air ascent. Methods: 157 participants (median age, 22 years) were enrolled and passively ascended primarily by air from 500 m to 3,650 m, spending approximately 3.5 hours. Participants were classified as AMS+ and AMS- based on their Lake Louise AMS score (LLS) after 24 hours at 3,650 m. Measurements included heart rate (HR), blood pressure, pulse oximeter saturation (SpO Results: The prevalence of AMS at 3,650 m was 45%. AMS+ participants had higher HR and RDW and lower SpO Conclusion: The findings suggest that elevated RDW-CV is linked to an increased risk of AMS among Chinese young men primarily undergoing air ascent to 3,650 m.
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