ReviewJournal of arrhythmia2026
Lead-Related and Procedural Outcomes of His Bundle Pacing Versus Left Bundle Branch Area Pacing in Patients Undergoing Atrioventricular Node Ablation: A Systematic Review and Meta-Analysis.
Review in Journal of arrhythmia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: In patients undergoing atrioventricular node ablation (AVNA), permanent pacing is required, making lead performance and procedural durability important. His bundle pacing (HBP) and left bundle branch area pacing (LBBAP) are physiologic pacing strategies used in this setting, but comparative evidence remains limited. Methods: We searched PubMed/MEDLINE and Embase through January 31, 2026, for comparative studies of HBP versus LBBAP in adults undergoing AVNA. The primary outcome was chronic lead-related dysfunction, defined as clinically significant chronic capture-threshold elevation. Secondary outcomes were AVNA procedural duration and atrioventricular nodal reconduction requiring repeat ablation. Random-effects models generated pooled risk ratios (RRs) or mean differences (MDs). Certainty was assessed using GRADE. Results: Three observational studies comprising 434 patients were included. Two studies ( Conclusions: Among patients undergoing AVNA, LBBAP was associated with more favorable lead-related and procedural outcomes than HBP across available observational studies. Because evidence is limited by small cohorts, sparse events, and nonrandomized designs, these findings should be considered hypothesis-generating. Trial Registration: This systematic review was registered in the PROSPERO database (registration number: CRD420261424072).
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